Abstract:Background: Fatigue is the main complaint exiting in patients with primary Sjögren's Syndrome (pSS) but rarely addressed.Patients described it as an uncontrollable symptom of lack of energy, which has negative impacts on health related quality of life. To date, many studies have demonstrated that cytokines, depression, sleep and endocrine disturbance interrelated with pSS-related fatigue. However, the pathogenesis remains unclear. With a long history, Traditional Chinese Medicine (TCM) as alternative therapy h… Show more
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