Fatigue in sarcoidosis: Detection and treatment

Vucinic, Violeta; Stojković, Mirjana; Milenković, Branislava; Videnović-Ivanov, Jelica; Škodrić-Trifunović, Vesna; Zugic, Vladimir; Gvozdenovic, Branislav; Milovanovic, A.N.; Filipović, Snežana

doi:10.2298/sarh1202104v

Cited by 5 publications

(2 citation statements)

References 28 publications

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“…Among patients with sarcoidosis, the disease course is highly variable, and thus patients may present with a wide array of clinical manifestations and multiple non-specific symptoms. Fatigue is an integral part of the clinical picture of sarcoidosis [4]. Sarcoidosis can involve any organ, with pulmonary involvement being the most common one.…”

Section: Discussionmentioning

confidence: 99%

Gastric sarcoidosis

Kasikovic-Lecic

Vucinic²,

Panjković

et al. 2017

Srp Arh Celok Lek

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Introduction Sarcoidosis is a systemic disease with a 90% predilection for the lungs, but any organ can be involved. Gastric sarcoidosis may be a component of a generalized process, while isolated gastric sarcoidosis is very rare. Case Outline We describe a rare case of biopsy-proven gastric sarcoidosis in a 45-year-old woman with pulmonary sarcoidosis in remission, and highlight the importance of gastroscopy and biopsy to confirm the diagnosis. Her optimal response to anti-acid therapy required no alternate (glucocorticoid) therapy. We briefly review the clinical, diagnostic, and therapeutic aspects of gastric sarcoidosis. Conclusion Glucocorticoids remain the cornerstone of the sarcoidosis treatment, although it has been insufficiently documented by clinical trials. The decision to treat sarcoid patients with systemic glucocorticoids is largely based upon the severity of symptoms. The anti-acid therapy may be an alternative in milder cases, as demonstrated in our patient.

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Section: Discussionmentioning

confidence: 99%

Gastric sarcoidosis

Kasikovic-Lecic

Vucinic²,

Panjković

et al. 2017

Srp Arh Celok Lek

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“…Patients may also develop symptoms related to extrapulmonary organ involvement. In addition, sarcoidosis may cause constitutional symptoms such as fatigue, fever, anorexia, weight loss, generalized weakness, and pain that are not attributable to involvement of any specifi c organ [2,3].…”

Section: Introductionmentioning

confidence: 99%

Psychometric characteristics of the Serbian version of the Licester Cough Questionnaire in sarcoidosis patients

Gvozdenovic¹,

Mihailović-Vučinić²,

Vukovic³

et al. 2019

Hosp Pharm Int Multi J

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Introduction: Cough is frequent symptom in sarcoidosis and there are no specifi c tools for measurement of its severity in Serbia. Aim: The goal of this study was to translate and validate the Serbian version of the Leicester Cough Questionnaire (LCQ) in a population of sarcoidosis patients. Methods: After the LCQ forward-backward translation process, in the cross-sectional study in 275 (180 female) sarcoidosis patients Serbian version of the LCQ was administered together with other standardized instruments for measurement of Patient Reported Outcomes (PROs)-symptoms of dyspnea (assessed by MRC and Borg scales) and fatigue (measured by Fatigue Assessment Scale and List of Daily Activities), and patients' health status (assessed by generic tool-15D). Pulmonary function tests (spirometry and diff using capacity for carbon monoxide) were also measured. Results: Serbian LCQ version showed excellent internal consistency (Cronbach's alpha of its diff erent scores ranged between 0.901 for physical domain and 0.951 for the total score). Concurent validity assessed by correlations of all LCQ scores with other PROs and pulmonary function tests was very good, since all these correlations were statistically signifi cant. Conclusions: Our results confi rmed that the Serbian version of LCQ is a valid instrument to monitor the infl uence of chronic cough on quality of life in sarcoidosis patients.

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