This paper investigates the crack and mechanical behavior of CFRP plate-reinforced bridge roof under high temperature with different anchoring measures. Six CFRP-reinforced test beams with different anchoring schemes were designed and constructed. The beam specimens, after the high temperature effects, were tested under four-point bending loads. The crack propagation, beam deflection, mid-span strain and the damage modes were observed and recorded until failure. The stiffness variation and the debonding failure mechanism of the test beams were comparatively investigated. The results indicate that the debonding bearing capacity of the specimens can be improved by the additional anchoring measures. The concrete shrinkage at the crack and the average crack spacing are more effectively reduced, when the additional anchoring measures are placed at the mid-span and the support position. In addition, a theoretical model is proposed for calculating the intermediate crack debonding bearing capacity. Based on the comparative analysis of various models and test results, it is shown that the proposed model could accurately calculate the intermediate crack debonding bearing capacity of the test specimens.