Fatores Associados Ao Número De Consultas Pré-Natais De Mulheres Tabagistas E Não Tabagistas Atendidas Em Hospitais De Porto Alegre (Rs), Brasil

Ferreira, Amanda Pereira; Bernardi, Juliana Rombaldi; Ferreira, Charles Francisco; Santos, Diego Almeida dos; Santos, Karen Ferreira dos; Pereira, Lívia Willborn; Wainer, Mariana; Ferreira, Pâmela Kremer; Bosa, Vera Lúcia; Silva, Clécio Homrich da; Goldani, Marcelo Zubarán

doi:10.18310/2446-4813.2016v2n2p167-178

Cited by 5 publications

(6 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…64 Nicotine, an alkaloid of the heterocyclic amine group extracted from the plant Nicotiana tabacum organic tissues 64,65 and, when consumed during pregnancy, increases the risk of complications not only for mothers but also for the fetuses. 2 Smoking mothers present considerable risks related to the higher incidence of miscarriage, placental abruption, premature birth, births of newborns with low body weight, and congenital anomalies. 66 In the present study, pregnant rats were exposed to nicotine throughout the pregnancy and lactation to simulate the exposure that occurred in moderately smoking mothers.…”

Section: Discussionmentioning

confidence: 99%

“…1 Smoking during pregnancy presents risks for mother and fetus health. 2 Indeed, cigarettes are responsible for 20% of cases of neonates showing low birth weight, 8% of premature births, and 5% of all perinatal deaths. 3 Nicotine is the main component of cigarettes and, therefore, one of the most legally used drugs worldwide.…”

Section: Introductionmentioning

confidence: 99%

“…Approximately 22.5% of the world's population are cigarette smokers 1 . Smoking during pregnancy presents risks for mother and fetus health 2 . Indeed, cigarettes are responsible for 20% of cases of neonates showing low birth weight, 8% of premature births, and 5% of all perinatal deaths 3 …”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Resveratrol reverses male reproductive damage in rats exposed to nicotine during the intrauterine phase and breastfeeding

et al. 2022

View full text Add to dashboard Cite

Background: Nicotine leads to reproductive changes culminating in male infertility and subfertility. Resveratrol, a polyphenol, is a biological modulator. Sirtuin 1 (SIRT1) protein can positively act on male reproduction, and its expression can be affected by nicotine and modulated by resveratrol. Objectives:The capability of resveratrol to reverse the reproductive damage in adult male offspring, which was nicotine-exposed during the intrauterine phase and breastfeeding, was investigated.Materials and methods: Four groups were established with male offspring born from nicotine-exposed and non-exposed rat dams during pregnancy and lactation. Fortyeight male Wistar rats were distributed into four groups: sham control (SC), resveratrol (R), nicotine (N), and nicotine + resveratrol (NR). Rat dams of the N and NR offspring were exposed to nicotine (2 mg/kg/day) during pregnancy and lactation using a subcutaneously implanted minipump. The offspring of the R and NR groups received resveratrol (300 mg/kg of body weight, gavage) for 63 days from puberty. At 114 days of age, the male rats were euthanized.Results: Nicotine did not alter the body weight, biometry of reproductive organs, or quantitative sperm parameters of adult offspring but caused an evident worsening of all sperm qualitative parameters studied. Daily treatment with resveratrol from puberty up to adulthood improved all qualitative sperm parameters significantly, leading some of them close to the control values. Resveratrol also improved the morphological integrity and expression of SIRT1 in the seminiferous epithelium of nicotineexposed offspring. Conclusion and Discussion:Resveratrol reversed the male reproductive damage caused by nicotine. Nicotine crosses the blood-placental membrane and is present in the breast milk of mothers who smoke. Resveratrol restored the altered reproductive parameters in the male adult offspring that were nicotine-exposed during intrauterine life and breastfeeding. The epigenetic modulating action of resveratrol can be involved in this nicotine damage reversion. Resveratrol may be a promising candidate to be investigated regarding the adjuvant strategies in the treatment of male infertility.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Resveratrol reverses male reproductive damage in rats exposed to nicotine during the intrauterine phase and breastfeeding

et al. 2022

View full text Add to dashboard Cite

show abstract

“…According to a study carried out by Ferreira et al 20 in the city of Porto Alegre, Brazil, aiming to analyze the factors associated with the number of prenatal consultations in smoking and non-smoking women, smoking during pregnancy was especially associated with the most unfavorable socioeconomic conditions, reinforcing the need for quali ed prenatal care, aimed at identifying vulnerabilities and supporting these pregnant women. The number of prenatal visits is associated with unfavorable maternal and child outcomes.…”

Section: Discussionmentioning

confidence: 99%

The weight gain influence of pregnant women under different clinical conditions on weight at the birth of newborns.

Mariot

Kretzer

Nunes

et al. 2020

Preprint

Self Cite

View full text Add to dashboard Cite

BACKGROUND: This study evaluate the influence of weight gain of pregnant women under different clinical conditions (Tobacco, Diabetes mellitus (DM), Hypertension, Intrauterine growth restriction (IUGR) and Control) on the birth weight of newborns. METHODS: This is an observational, longitudinal study nested in a prospective controlled cohort and conducted from 2011 to 2016 in three hospitals in the city of Porto Alegre (Brazil). Sociodemographic, prenatal (maternal gestational weight gain, among others) and perinatal (birth weight) data from 372 mother-child pairs were analyzed. Pearson's correlation was used to verify the relationship between gestational weight gain and birth weight. Multivariate regression was performed to determine the association between maternal weight gain in the presence of various health conditions and birth weight. RESULTS: There were no statistical differences in gestational weight gain in different health condition groups (p=0.092). However, women in the Hypertension group had a tendency to gain more weight (p = 0.097). Mothers in the intrauterine growth restriction group gained less weight. A positive correlation was observed between gestational weight gain and birth weight in the Tobacco (p = 0.003) and Control (p =0.001) groups, which remained positive only in the Control group after adjustment (p<0.004). CONCLUSIONS: Only weight gain in pregnant women without clinical changes during pregnancy seemed to influence the weight of the newborn. It is assumed that other factors, such as metabolic or nutritional, present among smoking, diabetes mellitus, hypertensive or with intrauterine growth restriction pregnant women have different modulations on the intrauterine environment and, therefore, exert a different influence on fetal growth.

show abstract

“…The pregnant woman’s knowledge of her health condition (DM or SAH) may determine the demand for more frequent care than the others. A study published with data from this cohort, using MS and control groups, found that the number of prenatal consultations was negatively influenced by MS during pregnancy and by the number of children, along with a positive correlation regarding maternal age [31]. In the general analysis of groups, a higher frequency of more than 7 visits (67%) was observed, which corroborates with data observed in a previous study, evidencing an increase in prenatal coverage in Porto Alegre [32].…”

Section: Discussionmentioning

confidence: 99%

Impact of Perinatal Different Intrauterine Environments on Child Growth and Development: Planning and Baseline Data for a Cohort Study

Werlang¹,

Bernardi²,

Nunes³

et al. 2019

JMIR Res Protoc

Self Cite

View full text Add to dashboard Cite

BackgroundSeveral studies have shown that exposure of the fetus and newborn to prenatal and perinatal events, respectively, may influence the health outcomes of the child throughout their life cycle.ObjectiveThis study aimed to increase the knowledge on the impact of different intrauterine environments on child growth and development, as we know that pregnancy and early years are a window of opportunity for health promotion and prevention interventions of diseases.MethodsThe recruitment occurred 24 to 48 hours after delivery and involved mothers and their newborns in 2 public hospitals in Porto Alegre, Brazil, from December 2011 to January 2016. The mothers-newborns dyads were allocated to 5 groups: diabetes mellitus, mothers with a clinical diagnosis of diabetes; systemic arterial hypertension (SAH), mothers with a clinical diagnosis of systematic arterial hypertensive disease during pregnancy; maternal smoking, mothers who smoked at any moment of gestation; small for gestational age (SGA), mothers with SGA newborns because of intrauterine growth restriction; and control, mothers without the clinical characteristics previously mentioned. Several protocols and anthropometric measurements were applied in the interviews at immediate postpartum and 7 and 15 days and 1, 3, and 6 months after birth. For this study, we analyzed only data collected during postpartum interviews. The statistical analyses were performed using Pearson chi-square test, Mann-Whitney test, or Kruskal-Wallis test with Dunn post hoc. The significance level was set at 5%. The Hospital Ethics and Research Committees approved the study.ResultsOf the 485 eligible mothers-newborns dyads, 400 agreed to participate (82.5%, 400/485). As expected, newborns from the SGA group had significantly lower birth weight, smaller stature, and lower cephalic perimeter (P<.001). This group also had the highest percentage of primiparous women in comparison with other groups (P=.005) except for control. Mothers from the SAH group had the highest mean age, the highest percentage of cesarean sections, and presented greater gestational weight gain.ConclusionsIn this study, we describe the planning and structure for the systematic follow-up of mother-newborn dyads in the first 6 months after birth, considering the important demographic and epidemiological transition scenario in Brazil. The results of this prospective longitudinal study may provide a better understanding of the causal mechanisms involved in health and life course disease related to different adverse intrauterine environments.

show abstract

Fatores Associados Ao Número De Consultas Pré-Natais De Mulheres Tabagistas E Não Tabagistas Atendidas Em Hospitais De Porto Alegre (Rs), Brasil

Cited by 5 publications

References 10 publications

Resveratrol reverses male reproductive damage in rats exposed to nicotine during the intrauterine phase and breastfeeding

Resveratrol reverses male reproductive damage in rats exposed to nicotine during the intrauterine phase and breastfeeding

The weight gain influence of pregnant women under different clinical conditions on weight at the birth of newborns.

Impact of Perinatal Different Intrauterine Environments on Child Growth and Development: Planning and Baseline Data for a Cohort Study

Contact Info

Product

Resources

About