Fatty acid composition of tail, subcutaneous and kidney fats of fat-tailed Awassi sheep

Al-Shabibi, M.M.A.; Juma, K. H.

doi:10.1017/s0021859600057725

Cited by 6 publications

(2 citation statements)

References 4 publications

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“…Previous research has suggested that sex hormones may influence the enzymatic synthesis of long-chain polyunsaturated fatty acids and has shown sex-specific differences in some outcomes [61]. The adipose tissue of the tail of sheep is mainly composed of triglycerides [62], which is a fat molecule formed by long-chain fatty acids and glycerin.…”

Section: Discussionmentioning

confidence: 99%

A Transcriptomic Study of the Tail Fat Deposition in Two Types of Hulun Buir Sheep According to Tail Size and Sex

Fan

Hou

Sahana

et al. 2019

Animals

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Simple SummaryBased on tail types, Hulun Buir sheep were divided into two lines including small and big fat-tailed, but these two lines have similar genetic background. In this study, we investigated the morphology and transcription level differences of tail fat between these two lines. The RNA-seq analyses indicated several differentially expressed genes when compared between sexes or two tail sizes. Interestingly, we also found an obvious sex difference in the fat metabolism in Hulun Buir sheep. Two different co-expression networks were only shown either in male or in female sheep. Our findings will provide theoretical background in understanding the genetic mechanism of fat deposition in sheep.AbstractHulun Buir sheep of similar genetic background were divided into two lines based on tail types: Small- and big fat-tailed. To explore the molecular mechanism of fat deposition in sheep tails, we firstly evaluated the morphology and transcription level differences of tail fat between these two lines. RNA-Seq technology was used to identify differentially expressed genes (DEGs) in phenotypic extremes of tail sizes. Five comparisons were performed taking into account two factors, sex and tail type. We screened out 373 DEGs between big-tailed and small-tailed Hulun Buir sheep, and 775 and 578 DEGs between two types of tails in male and female sheep, respectively. The results showed an obvious sex difference in the fat metabolism in sheep based on gene ontology (GO), pathway, and network analyses. Intriguingly, there were two different co-expression networks only respectively shown in male and female sheep, which were insulin-related network acting on upstream pathways and PPARG-related network effect in downstream pathways. Furthermore, these two networks were linked by a classic pathway of regulating adipogenesis. This is the first study to investigate the sex differences of fat metabolism in domestic animals, and it demonstrates a new experimental way to study fat metabolism. Our findings will provide theoretical background in understanding the tail-size phenotype in sheep and can be exploited in breeding small-tailed sheep.

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Section: Discussionmentioning

confidence: 99%

A Transcriptomic Study of the Tail Fat Deposition in Two Types of Hulun Buir Sheep According to Tail Size and Sex

Fan

Hou

Sahana

et al. 2019

Animals

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“…The trend to have increased 18:1 cis- 9 in tail fat of animals under feed restriction cannot be explained by the increased lipogenic and stearoyl-CoA desaturase activity and thus might be indicative that 18:1 cis- 9 might be preferential retained during mobilization probably to ensure a low melting point for tail fat. In fact, reviewing published fatty acid profiles of tail fat depots, it is clear that this depot presents higher 18:1 cis- 9 content than other fat depots [8], [14], [15]. Indeed, the unsaturated fatty acid, BCFA and odd-numbered fatty acids are recognized to largely contribute to lower lamb fat melting points [16].…”

Section: Discussionmentioning

confidence: 99%

Does the Fat Tailed Damara Ovine Breed Have a Distinct Lipid Metabolism Leading to a High Concentration of Branched Chain Fatty Acids in Tissues?

Alves¹,

Bessa²,

Quaresma³

et al. 2013

PLoS ONE

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Fat tailed sheep breeds are known for their adaptation to nutritional stress, among other harsh production conditions. Damara sheep, native to Southern Africa, have recently been exported to other areas of the world, particularly Australia, aiming to produce lamb in semi-arid regions. Damaras have a unique hanging fat tail, a fat depot able to be mobilized under nutritional stress. In this article we perform an in-depth characterization of the fatty acid profiles of the fat tail in underfed and control Damara rams. Profiles were very similar between experimental groups, with the exception of palmitic acid (16:0) that was lower (P = 0.014) in underfed animals. However, the most striking result was the very high proportions of non-terminal branched chain fatty acids found in the fat tail adipose tissue, as well as the gastrocnemius muscle of Damara rams. The muscle of Dorper and Merino rams used in the same experiment did not present non-terminal branched chain fatty acids, suggesting that Damara rams have a unique lipid metabolism. Herein, we interpret this trait relating it to a higher ability of Damara sheep to digest fibrous fodder and to putative differences in the propionate metabolism by comparison to other sheep breeds.

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The composition, structure and function of lipids in the tissues of ruminant animals

Christie

1978

Progress in Lipid Research

151

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Fatty acid composition of tail, subcutaneous and kidney fats of fat-tailed Awassi sheep

Cited by 6 publications

References 4 publications

A Transcriptomic Study of the Tail Fat Deposition in Two Types of Hulun Buir Sheep According to Tail Size and Sex

A Transcriptomic Study of the Tail Fat Deposition in Two Types of Hulun Buir Sheep According to Tail Size and Sex

Does the Fat Tailed Damara Ovine Breed Have a Distinct Lipid Metabolism Leading to a High Concentration of Branched Chain Fatty Acids in Tissues?

The composition, structure and function of lipids in the tissues of ruminant animals

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