Fatty Infiltration (Lipomatosis) of the Auriculoventricular Bundle of His, With Sudden Unexpected Death

Implications of Marked Fatty Infiltration Around and In the Atrophic Atrioventricular Node in Elderly Patients With Permanent Pacemaker Implantation for Symptomatic Sick Sinus Syndrome

“…31,32 Although this replacement by adipose tissue, lipomatosis, is quite regularly found in the AV bundle system of elderly people, it is not extensive enough to lead to clinical manifestation. 33 Especially in the approaches to the AVN, however, the connections between the superficial transitional cells and the AVN can become considerably attenuated as a consequence of the fat deposition related to aging. 34 In addition, the presence of large amounts of fat between myocardial fibers may produce muscle atrophy or be a replacement for degenerated tissue.…”