2014
DOI: 10.1016/j.kjms.2014.05.007
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Fatty liver‐induced changes in stereotypic behavior in rats and effects of glucagon‐like peptide‐1 analog on stereotypy

Abstract: Although understanding the relation between psychotic behavior and immune abnormalities has been the focus of research for many years, it remains to be elucidated whether the changes in cytokine levels are part of etiology or a result of the stress associated with the disorder. In accordance with previous studies on changes in cytokine levels due to metabolic changes and psychosis, we hypothesized that fatty liver may potentiate apomorphine-induced stereotypy in a rodent model and that a synthetic glucagon-lik… Show more

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Cited by 5 publications
(2 citation statements)
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“…Their results are in agreement with our findings about fetal liver tissue. Since the liver is one of the most complex and vital organs and its primary function is detoxification of absorbed substances from the digestive system before their distribution into the systemic circulatory system ( 26 ), Diazinon’s in vitro and in vivo degradation rate of metabolites in the liver requires further research ( 27 ). The exposure to OPCs during pregnancy is an important factor because it affects two organisms - the mother and the fetus ( 28 - 30 ).…”
Section: Discussionmentioning
confidence: 99%
“…Their results are in agreement with our findings about fetal liver tissue. Since the liver is one of the most complex and vital organs and its primary function is detoxification of absorbed substances from the digestive system before their distribution into the systemic circulatory system ( 26 ), Diazinon’s in vitro and in vivo degradation rate of metabolites in the liver requires further research ( 27 ). The exposure to OPCs during pregnancy is an important factor because it affects two organisms - the mother and the fetus ( 28 - 30 ).…”
Section: Discussionmentioning
confidence: 99%
“…In the treatment of stroke and neurodegenerative disorders such as AD, PD, amyotrophic lateral sclerosis, autism, schizophrenia, and other diseases such as diabetic retinopathy, ocular hypertension, and glaucoma, GLP-1 and GLP-1R have demonstrated remarkable neuroprotective effectiveness [3,[46][47][48][49][50].…”
Section: Neuroprotective Properties Of Glucagon-like Peptide-1mentioning
confidence: 99%