ABSTRACT. The Las Lozas volcanic sequence, which crops out at northwestern border of the Famatina belt-southeastern Puna, NW Argentina, is constituted mainly by rhyolites and a lesser volume of basalts and trachytes, and volcanoclastic deposits. These rocks, previously considered of Early Paleozoic age, are now assigned to the Lower Pennsylvanian (320 Ma U-Pb age). They represent a bimodal volcanic succession that plot in the subalkaline/tholeiitic (rhyolites), alkaline basalts (basalts) and alkaline (trachytes) fields on the total alkali-silica diagram. The basalts display features comparable to transitional MORB and within-plate tholeiites, with contributions from a mantle source affected by crustal contamination. The acid members also show geochemical affinities to within-plate magmas, and their composition suggest a derivation from continental crustal material with mantle source interaction or a juvenile essentially mantle derived crust. The 320 Ma age from the Las Lozas volcanic succession as well as the 342 and 348 Ma U-Pb ages, from rocks in the nearby Cazadero Grande section, to the south, and the U-Pb ages from Sierra Pampeanas granites (332-357 Ma) highlight the importance achieved by Carboniferous magmatic activity in that region, framed between 320 and 350 Ma. Low strontium initial ratios from the Las Lozas (0.70479-0.70164) indicate a predominant contribution by a juvenile component, while the ratios in the nearby Cazadero Grande (0.71433-0.71233) and Sierras Pampeanas granites (0.717 to 0.7124) point to an input by enriched sources with restricted contribution of a mantle component. Nd isotopes from a basalt from the Las Lozas section (ε Nd(320) with +3.11, T DM with 774.6 Ma) indicates a possible asthenospheric source, with evidence for some mixture between juvenile and reworked crustal material. In contrast Sr-Nd isotopes in a rhyolite from Cazadero Grande (εNd (t) of -2.91 and -0.3, T DM of 1.09 and 1