Favorable association of polyphenol-rich diets with lung function: Cross-sectional findings from the Moli-sani study

Pounis, George; Arcari, Antonella; Costanzo, Simona; Castelnuovo, Augusto Di; Bonaccio, Marialaura; Persichillo, Mariarosaria; Donati, Maria Benedetta; Gaetano, Giovanni de; Iacoviello, Licia

doi:10.1016/j.rmed.2017.12.007

Cited by 30 publications

(27 citation statements)

References 44 publications

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“…In a recent randomized trial in COPD patients, supplementation with flavonoids in the form of oligomeric pro-anthocyanidins extracted from grape seeds was effective in improving oxidative stress and lipid profile, but not lung function parameters after 8 weeks [75]. More recent observational findings in a Mediterranean population confirmed protective effects of the intake of various polyphenol classes on pulmonary function parameters [76]. In a cross-sectional study in 267 Spanish COPD patients, dietary intakes of vitamin E as well as vegetables and olive oil, rich in vitamin E and polyphenols, have been shown to be inversely correlated with serum markers of oxidative stress, especially in current smokers [77].…”

Section: Individual Foods and Nutrients Lung Function And Copdmentioning

confidence: 99%

Role of Diet in Chronic Obstructive Pulmonary Disease Prevention and Treatment

et al. 2019

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Chronic obstructive pulmonary disease is one of the leading causes of morbidity and mortality worldwide and a growing healthcare problem. Identification of modifiable risk factors for prevention and treatment of COPD is urgent, and the scientific community has begun to pay close attention to diet as an integral part of COPD management, from prevention to treatment. This review summarizes the evidence from observational and clinical studies regarding the impact of nutrients and dietary patterns on lung function and COPD development, progression, and outcomes, with highlights on potential mechanisms of action. Several dietary options can be considered in terms of COPD prevention and/or progression. Although definitive data are lacking, the available scientific evidence indicates that some foods and nutrients, especially those nutraceuticals endowed with antioxidant and anti-inflammatory properties and when consumed in combinations in the form of balanced dietary patterns, are associated with better pulmonary function, less lung function decline, and reduced risk of COPD. Knowledge of dietary influences on COPD may provide health professionals with an evidence-based lifestyle approach to better counsel patients toward improved pulmonary health.

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Section: Individual Foods and Nutrients Lung Function And Copdmentioning

confidence: 99%

Role of Diet in Chronic Obstructive Pulmonary Disease Prevention and Treatment

et al. 2019

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“…Studies in mice model and human volunteers showed their presence in numerous tissues (83,84). They are also found to be associated with better pulmonary functions in epidemiological studies (85). These findings are encouraging to consider polyphenols as an integral part of nutritional immunity particularly innate immune response, and tea being widely consumed drink is an important and unique source of essential micronutrients and vitamins as well.…”

Section: Discussionmentioning

confidence: 64%

Tea Bioactive Modulate Innate Immunity: In Perception to COVID-19 Pandemic

Chowdhury

Barooah

2020

Front. Immunol.

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Innate immunity impairment led to disruption in cascade of signaling pathways upregulating pro-inflammatory cytokines, diminish interferons, depleted natural killer cells and activate reactive oxygen species production. These conditions severely affected body's ability to fight against infectious diseases and also plays a pivotal role in disease progression. Here, in emphasis is on nutritional immunity for regulating effective innate immune response for combating against infectious diseases like novel coronavirus disease (COVID 19). Drawing from discoveries on in-vitro experiments, animal models and human trials, tea polyphenols, micronutrients, and vitamins has the potential to modulate and enhance innate immune response. This article provides a comprehensive review on tea (Camellia sinensis L) infusion (a hot water extract of dried processed tea leaves prepared from young shoots of tea plant) as an innate immunity modulator. Tea infusion is rich in polyphenols; epigallocatechin gallate (EGCG) and theaflavin (TF), major green and black tea polyphenols, respectively. Studies showed their immunomodulatory competence. Tea infusions are also rich in alkaloids; caffeine and its intermediates, theophylline and theobromine, which have anti-inflammatory properties. Tea plant being an acidophilic perennial crop can accumulate different micronutrients, viz., copper (Cu), iron (Fe), manganese (Mn), selenium (Se), and zinc (Zn) from growing medium, i.e., from soil, which led to their considerable presence in tea infusion. Micronutrients are integral part of innate immune response. Overall, this review presents tea infusion as an important source of nutritional immunity which can enhance innate immune response in order to mitigate the unprecedented COVID-19 pandemic.

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“…Polyphenols, which include phenolic acids, flavonoids, stilbenes, lignans and secoiridoids, seem to positively influence the human gut microbiota through inhibition of potential pathogens such as Helicobacter pylori and Staphylococ cus species and favoring the enrichment of other potential beneficial species, such as Lactobacillus and Bifidobacteria [144][145][146][147][148][149]. Polyphenols have also been associated with chronic disease, cancer and neurodegenerative disease prevention [150][151][152][153].…”

Section: Nutrition and Dietary Supplements Could Affect Microbiota Dymentioning

confidence: 99%

May nutrients and dietary supplements influence the gut-lung microbiota axis in chronic obstructive pulmonary disease and exacerbations?

Conte

Toraldo²

2020

Arch Med Sci

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There is increasing evidence that microbial community structure and diversity are associated with disease severity and clinical outcomes, both in stable chronic obstructive pulmonary disease (COPD) and in exacerbations. New evidence has confirmed that the gut-lung axis-the cross-talk between the gut and the lung-is a bi-directional condition that is a continuous blood communication between the two sits that, in this way, would be able to modulate each other's local immune response and the composition of the respective microbiota. However, although it is clear that the gut microbiota influences inflammation in the peripheral system, what happens in the lung is still poorly understood. As malnutrition is an important factor in COPD, nutritional support might be a strong component of disease management and prevention. In this review, we tried to elucidate the role of diet and dietary supplementation affecting the lung microbiota with respect to stable COPD and exacerbation.

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Favorable association of polyphenol-rich diets with lung function: Cross-sectional findings from the Moli-sani study

Abstract: A higher overall polyphenol content of human diet was associated with better pulmonary function in a general population. The association might be partially mediated by WBC in men.

Cited by 30 publications

References 44 publications

Role of Diet in Chronic Obstructive Pulmonary Disease Prevention and Treatment

Role of Diet in Chronic Obstructive Pulmonary Disease Prevention and Treatment

Tea Bioactive Modulate Innate Immunity: In Perception to COVID-19 Pandemic

May nutrients and dietary supplements influence the gut-lung microbiota axis in chronic obstructive pulmonary disease and exacerbations?

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