Favorable Prognosis of Upper-Gastrointestinal Bleeding in 1041 Older Patients: Results of a Prospective Multicenter Study

Nahon, Stéphane; Nouël, O; Hagège, Hervé; Cassan, P; Pariente, Alexandre; Combes, Rémi; Kerjean, Alain; Doumet, Sylva; Cocq-Vezilier, Perrine; Tielman, Guillaume; Paupard, Thierry; Janicki, Eric; Bernardini, David; Antoni, M.; Haioun, Jajjia; Pillon, D.; Bretagnolle, Philippe

doi:10.1016/j.cgh.2008.02.064

Cited by 39 publications

(39 citation statements)

References 21 publications

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“…Markers of resource use and clinical outcomes in upper GI bleeding include LOS and cost, 39,40 and this study found that both LOS and cost increased with increasing AIMS65 scores. By calculating LOS and cost only for patients who survived the index hospitalization, this study demonstrated that there are increased costs related to the treatment of patients with higher AIMS65 scores that were not tied to end of life care.…”

Section: Los and Costsmentioning

confidence: 93%

A simple risk score accurately predicts in-hospital mortality, length of stay, and cost in acute upper GI bleeding

Saltzman

Tabak²,

Hyett

et al. 2011

Gastrointestinal Endoscopy

428

349

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Section: Los and Costsmentioning

confidence: 93%

A simple risk score accurately predicts in-hospital mortality, length of stay, and cost in acute upper GI bleeding

Saltzman

Tabak²,

Hyett

et al. 2011

Gastrointestinal Endoscopy

428

349

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“…It remains a major clinical problem because elderly patients tend to have more complications during hospitalization and mortality than younger patients 1e8 . However, in one report 9 , researchers found the mortality between the younger and older patients was no different, which may be due to more younger patients having upper GI bleeding related to portal hypertension, which raised the consideration that, if upper GI bleeding is causes by portal hypertension, such as esophageal variceal bleeding or gastric variceal bleeding, it may have different consequences between the older and younger patients.…”

Section: Introductionmentioning

confidence: 93%

“…Rupture of the gastric varices is responsible for 10%e15% of all variceal bleeding 11,12 . Although bleeding from gastric varices is less than from esophageal varices, it is often more severe and the mortality may reach up to 20%e40% 11,13 , which is much higher than the overall mortality rate of upper GI bleeding in older patients (6%e8.9%) 2,9 . There is no previous study that discusses gastric variceal bleeding between the older and younger patients, since older patients are bearing worse outcomes than younger patients in upper GI bleeding.…”

Section: Introductionmentioning

confidence: 99%

Gastric Variceal Bleeding in the Elderly

Wang

Chen

Lin

et al. 2012

International Journal of Gerontology

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s u m m a r yBackground: Upper gastrointestinal bleeding of all causes has a higher morbidity and mortality in older patients compared with younger patients. We retrospectively studied gastric variceal bleeding in older patients and compared the complications and outcomes of endoscopic variceal obliteration with younger patients. Methods: From August 2002 to August 2010, a total of 76 patients with gastric variceal bleeding who had received endoscopic variceal obliteration using Histoacryl as an adhesive agent by a single endoscopist were studied. Their chart records were obtained and reviewed with data collection. Patient demographics, laboratory parameters, etiology of liver cirrhosis, Child-Pugh classification, endoscopic findings, complications after endoscopic treatment, and mortality were gathered and analyzed. Results: A total of 26 (34.2%) of the 76 patients were older than 64 years. There were patients who were younger than 64 years who had more variceal bleeding as compared with the older patients. In older patient groups, women were more likely to have gastric variceal bleeding than their male counterparts. The most common type of gastric varices was gastroesophageal varices type 2 (GOV2). Significant difference existed in the etiology of cirrhosis between the two groups, with more hepatitis B and alcoholic hepatitis in the younger patients and more hepatitis C in the older patients. Significantly more Child-Pugh classification B and C cases were noticed in the younger patients. There were no significant differences of mortality and complications after treatment, including recurrent bleeding and sepsis, between the older and younger patients. Conclusion: There was no significant difference in outcomes after endoscopic treatment between the younger and the older patient groups. Endoscopic variceal obliteration using Histoacryl as an adhesive agent could be applied to treat older patients with gastric variceal bleeding just as it is for younger patients.

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“…The majority of cases reported are in stomach (25% to 60%) however other sites are esophagus terminal ileum, colon, meckel's diverticulum, omentum, mesentery, spleen, liver, papilla of vater, bladder, lung, lymphodes [11][12][13]. Since Poppi's publication in 1916, there have been only 30 more cases of HP worldwide [12,13]. In half of the reported cases, HP is seen to be localized close to the neck of the gallbladder [14].…”

Section: Discussionmentioning

confidence: 99%

Heterotopic Pancreatic Tissue in Gall Bladder: A Rare Entity

Gupta¹,

Tiwari²,

Lal³

et al. 2017

J Clin Case Rep

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Introduction: Pancreatic heterotopia is a rare pathological entity and its localization in gall bladder is extremely rare. It is mostly asymptomatic incidental finding and rarely gives rise to complications. It can be associated with incidental finding or can be symptomatic or may cause complication. Heterotopic pancreas (HP) also referred to as ectopic pancreas, pancreatic choristoma, or pancreatic rest, is defined as the aberrantly located pancreatic tissue in an anomalous location without any anatomic, vascular, or neural continuity with the main body of the normal pancreas. The most common location for HP is the duodenum, upper jejunum and stomach.

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Favorable Prognosis of Upper-Gastrointestinal Bleeding in 1041 Older Patients: Results of a Prospective Multicenter Study

Cited by 39 publications

References 21 publications

A simple risk score accurately predicts in-hospital mortality, length of stay, and cost in acute upper GI bleeding

A simple risk score accurately predicts in-hospital mortality, length of stay, and cost in acute upper GI bleeding

Gastric Variceal Bleeding in the Elderly

Heterotopic Pancreatic Tissue in Gall Bladder: A Rare Entity

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