Favourable 5-year postdischarge survival of comatose patients resuscitated from out-of-hospital cardiac arrest, managed with immediate coronary angiogram on admission

Sidéris, Georgios; Voicu, Sébastian; Yannopoulos, Demetris; Dillinger, Jean Guillaume; Adjedj, Julien; Deye, Nicolas; Guèye, Papa; Malissin, Isabelle; Logeart, Damien; Magkoutis, Nikolaos; Capan, Dragos Daniel; Makhloufi, Siham; Mégarbane, Bruno; Vivien, Benoît; Cohen‐Solal, Alain; Payen, Didier; Baud, Frédéric J.; Henry, Patrick

doi:10.1177/2048872614523348

Cited by 31 publications

(27 citation statements)

References 34 publications

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“…A more recent study by Sideris et al also showed similar survival rates after hospital discharge. 47 Our overall survival after five years was 85% regardless of intervention or rhythm. Combined MTH and PCI has been associated with better in-hospital outcomes in cohort studies.…”

Section: Discussionmentioning

confidence: 70%

Long-term outcome of patients after out-of-hospital cardiac arrest in relation to treatment: a single-centre study

Bergman

Hiemstra

Nieuwland

et al. 2015

European Heart Journal: Acute Cardiovascular Care

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In this integrated ST elevation myocardial infarction network survival and neurological outcome of selected patients with ROSC after OHCA and treated with PCI was good. There is insufficient evidence about the outcome of this approach, which has a significant impact on utilisation of resources. Good quality randomised controlled trials are needed. In selected patients successfully resuscitated after OHCA of presumed cardiac aetiology, we believe that a more liberal application of primary PCI may be considered in experienced acute cardiac referral centres.

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Section: Discussionmentioning

confidence: 70%

Long-term outcome of patients after out-of-hospital cardiac arrest in relation to treatment: a single-centre study

Bergman

Hiemstra

Nieuwland

et al. 2015

European Heart Journal: Acute Cardiovascular Care

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“…3,[26][27][28][29] On the prehospital field and immediately after admission, temperatures were measured with infrared tympanic thermometers. Subsequent temperature measurements were performed for each patient with a bladder probe (Foley urinary catheter with tip thermistor, Tyco Healthcare, Plaisir, France) and/or an esophageal probe (Mon-a-Therm Temperature Probe 400, Covidien, Mansfield, MA; Table I in the online-only Data Supplement).…”

Section: Protocol and Treatmentmentioning

confidence: 99%

Endovascular Versus External Targeted Temperature Management for Patients With Out-of-Hospital Cardiac Arrest

et al. 2015

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Background— Targeted temperature management is recommended after out-of-hospital cardiac arrest. Whether advanced internal cooling is superior to basic external cooling remains unknown. The aim of this multicenter, controlled trial was to evaluate the benefit of endovascular versus basic surface cooling. Methods and Results— Inclusion criteria were the following: age of 18 to 79 years, out-of-hospital cardiac arrest related to a presumed cardiac cause, time to return of spontaneous circulation <60 minutes, delay between return of spontaneous circulation and inclusion <240 minutes, and unconscious patient after return of spontaneous circulation and before the start of cooling. Exclusion criteria were terminal disease, pregnancy, known coagulopathy, uncontrolled bleeding, temperature on admission <30°C, in-hospital cardiac arrest, immediate need for extracorporeal life support or hemodialysis. Patients were randomized between 2 cooling strategies: endovascular femoral devices (Icy catheter, Coolgard, Zoll, formerly Alsius; n=203) or basic external cooling using fans, a homemade tent, and ice packs (n=197). The primary end point, that is, favorable outcome evaluated by survival without major neurological damage (Cerebral Performance Categories 1–2) at day 28, was not significantly different between groups (odds ratio, 1.41; 95% confidence interval, 0.93–2.16; P =0.107). Improvement in favorable outcome at day 90 in favor of the endovascular group did not reach significance (odds ratio, 1.51; 95% confidence interval, 0.96–2.35; P =0.07). Time to target temperature (33°C) was significantly shorter and target hypothermia was more strictly maintained in the endovascular than in the surface group ( P <0.001). Minor side effects directly related to the cooling method were observed more frequently in the endovascular group ( P =0.009). Conclusion— Despite better hypothermia induction and maintenance, endovascular cooling was not significantly superior to basic external cooling in terms of favorable outcome. Clinical Trial Registration— URL: http://www.clinicaltrials.gov . Unique identifier: NCT00392639.

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“…In a previous study, patients with OHCA due to ACS had better survival to discharge at fiveyear follow up than patients with OHCA due to other causes. 14 Increasing age was an independent predictor of inhospital mortality in our analysis despite contemporary care with PPCI utilising advanced interventional strategies and pharmacotherapies. This finding is consistent with a previous observation that cardiopulmonary resuscitation (CPR) was rarely effective for elderly patients (>70 years of age) with CA that are either out-of-hospital, not witnessed, or associated with asystole or EMD.…”

Section: Discussionmentioning

confidence: 65%

“…In a previous study, patients with OHCA due to ACS had better survival to discharge at five-year follow up than patients with OHCA due to other causes. 14…”

Section: Discussionmentioning

confidence: 99%

Outcomes following primary percutaneous coronary intervention in the setting of cardiac arrest: A registry database study

Kunadian

Bawamia

Maznyczka

et al. 2014

European Heart Journal: Acute Cardiovascular Care

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Favourable 5-year postdischarge survival of comatose patients resuscitated from out-of-hospital cardiac arrest, managed with immediate coronary angiogram on admission

Abstract: OHCA patients undergoing on-admission CA had a very favourable postdischarge survival. Patients with OHCA due to ACS had better survival to discharge at 5-year follow up than patients with OHCA due to other causes.

Cited by 31 publications

References 34 publications

Long-term outcome of patients after out-of-hospital cardiac arrest in relation to treatment: a single-centre study

Long-term outcome of patients after out-of-hospital cardiac arrest in relation to treatment: a single-centre study

Endovascular Versus External Targeted Temperature Management for Patients With Out-of-Hospital Cardiac Arrest

Outcomes following primary percutaneous coronary intervention in the setting of cardiac arrest: A registry database study

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