FDG-PET/CT as a post-treatment restaging tool in urothelial carcinoma: Comparison with contrast-enhanced CT

Kitajima, Kazuhiro; Yamamoto, Shingo; Fukushima, Kazuhito; Yamakado, Koichiro; Katsuura, Takayuki; Igarashi, Yoko; Kawanaka, Yusuke; Mouri, Miya; Hirota, Shun

doi:10.1016/j.ejrad.2015.12.017

Cited by 33 publications

(13 citation statements)

References 14 publications

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“…Regarding postchemotherapy radiological images, it is difficult to distinguish patients from those without remaining viable cancer. Although PET is promising in the postchemotherapy treatment decision regarding testicular seminoma [ 30 – 33 ], its role in urothelial carcinoma is investigational at present [ 34 , 35 ]. Surgical salvage without systemic chemotherapy is extremely rare.…”

Section: Indication Of Metastasectomy For Metastatic Urothelial Carcimentioning

confidence: 99%

Role of surgical consolidation in metastatic urothelial carcinoma

Abe

Matsumoto

Shinohara

2016

Current Opinion in Urology

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Purpose of reviewSince the development of systemic combination chemotherapy, postchemotherapy extirpation has been performed in selected patients mainly with locally advanced and/or initially unresectable bladder cancer, and, in very selected patients, surgical consolidation for visceral metastases has also been performed. The purpose of this article was to review and summarize the current evidence for the role of surgical consolidation in metastatic urothelial carcinoma.Recent findingsThe role of metastasectomy has not yet been examined in a randomized setting. In terms of locally advanced and/or node-positive bladder cancer, studies further support the benefit of surgical consolidation, especially after a favorable response to systemic chemotherapy. Regarding metastasectomy for visceral metastasis, recent evidence suggested that lung metastases (ideally small solitary lesions) are a good indication.SummaryPatients with a good response to chemotherapy, limited nodal/pulmonary disease, and a favorable performance status are good candidates for surgical consolidation. Careful patient selection is mandatory.

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Section: Indication Of Metastasectomy For Metastatic Urothelial Carcimentioning

confidence: 99%

Role of surgical consolidation in metastatic urothelial carcinoma

Abe

Matsumoto

Shinohara

2016

Current Opinion in Urology

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“…Primary evaluation of upper UTUC on 18F‐FDG‐PET/CT is often limited because of the obscuring effect caused by high urinary activity, particularly if the upper UTUC is small or flat . However, 18F‐FDG‐PET/CT might be helpful in the detection of nodal or distant metastasis for staging, as well as for post‐treatment restaging and recurrent disease assessment …”

Section: F‐fdg‐pet/ct For Upper Utuc Stagingmentioning

confidence: 99%

“…34,35 However, 18F-FDG-PET/CT might be helpful in the detection of nodal or distant metastasis for staging, as well as for posttreatment restaging and recurrent disease assessment. 36,37 Pitfalls Upper UTUC can manifest itself in a variety of appearances, including papillary lesions, focal wall thickening with enhancement or infiltrative lesions. Even small lesions that protrude into the lumen can be easily detected as defects in excretoryphase images of CTU under a wide window width, as in bone conditions.…”

Section: F-fdg-pet/ct For Upper Utuc Stagingmentioning

confidence: 99%

Clinical staging of upper urinary tract urothelial carcinoma for T staging: Review and pictorial essay

et al. 2019

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Upper urinary tract urothelial carcinoma is staged using the TNM classification of malignant tumors. Preoperative TNM is important for treatment planning. Computed tomography urography is now widely used for clinical survey of upper urinary tract carcinoma because of its diagnostic accuracy. Computed tomography urography is recommended as the first‐line imaging procedure in several guidelines. Several reports stated that computed tomography urography is also useful for staging. However, no educational and practical reviews detailing the T staging of upper urinary tract urothelial carcinomas using imaging are available. We discuss the scanning protocol, T staging using computed tomography urography, limitations, magnetic resonance imaging, computed tomography comparison and pitfalls in imaging of upper urinary tract urothelial carcinoma. A recent study reported the high diagnostic accuracy of computed tomography urography with respect to T3 or higher stage tumors. To date, images that show a Tis–T2 stage have not been reported, but various studies are ongoing. Although magnetic resonance imaging has lower spatial resolution than computed tomography urography, magnetic resonance imaging can be carried out without radiation exposure or contrast agents. Magnetic resonance imaging also offers the unique ability of diffusion‐weighted imaging without contrast agent use. Some researchers reported that diffusion‐weighted imaging is useful not only for detecting lesions, but for predicting the T stage and tumor grade. We recommend the appropriate use of computed tomography and magnetic resonance while considering the limitations of each modality and the pitfalls in upper urinary tract urothelial carcinoma imaging.

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“…[ 63 ] PET/CT is also more accurate than CECT for detecting local and distant recurrence postsurgery. [ 64 ]…”

Section: Pelvic and Ureteric Cancersmentioning

confidence: 99%

PET-CT and PET-MR in urological cancers other than prostate cancer: An update on state of the art

2018

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Hybrid positron emission tomography with computed tomography (PET/CT) and magnetic resonance imaging (PET/MRI) have enabled the combination of morphologic and functional imaging with the promise of providing better information in guiding therapy. Further advance has been made in the past decade with the development of newer radiotracers and optimization of the technical aspects. We performed a search in PubMed, Scopus, and Google Scholar for peer-reviewed literature concerning the advances and newer developments in the imaging of nonprostate urologic cancers between 2005 and 2017. This review aims at summarizing the current evidence on PET imaging in nonprostate urologic cancers and their impact on the diagnosis, staging, prognostication, response assessment, and restaging of these malignancies. However, much of the evidence is still in infancy and has not been incorporated into routine management or the practice guidelines of National Comprehensive Cancer Network or European Society for Medical Oncology (ESMO).

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FDG-PET/CT as a post-treatment restaging tool in urothelial carcinoma: Comparison with contrast-enhanced CT

Cited by 33 publications

References 14 publications

Role of surgical consolidation in metastatic urothelial carcinoma

Role of surgical consolidation in metastatic urothelial carcinoma

Clinical staging of upper urinary tract urothelial carcinoma for T staging: Review and pictorial essay

PET-CT and PET-MR in urological cancers other than prostate cancer: An update on state of the art

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