FDG-PET in diagnostic work-up of pulmonary artery sarcomas

Tueller, C; Biner, Reta Fischer; Minder, S; Gugger, Matthias; Stoupis, Christoforos; Krause, Thomas; Carrel, T; Schmid, Ralph A.; Vock, Peter; Nicod, Laurent P.

doi:10.1183/09031936.00114708

Cited by 31 publications

(16 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…There is only sparse data on the role of F-18 FDG PET(/CT) for the imaging of primary sarcomas of the great vessels, mainly in patients with pulmonary artery involvement. However, the few cases reported in the literature are promising [13-16]. Ito et al reported on three patients with pulmonary artery sarcomas and demonstrated that the mean SUV max of 7.6 was significantly higher than in patients with pulmonary embolism [13].…”

Section: Discussionmentioning

confidence: 99%

“…Wittram and Scott observed SUV max values in the range from 0.45 to 3.03 for acute pulmonary emboli, which is considerably lower than the SUV max values reported for pulmonary sarcomas [17]. Another small series of three patients was published by Tueller et al with an SUV max of 5.2 (reported only for one patient) [16]. Treglia et al recently reported an SUVmax of 13 for a primary pulmonary epitheloid angiosarcoma that presented as an intrapulmonary mass [18].…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Imaging features of primary Sarcomas of the great vessels in CT, MRI and PET/CT: a single-center experience

et al. 2013

View full text Add to dashboard Cite

BackgroundTo investigate the imaging features of primary sarcomas of the great vessels in CT, MRI and 18 F-FDG PET/CT.MethodsThirteen patients with a primary sarcoma of the great vessels were retrospectively evaluated. All available images studies including F-18 FDG PET(/CT) (n = 4), MDCT (n = 12) and MRI (n = 6) were evaluated and indicative image features of this rare tumor entity were identified.ResultsThe median interval between the first imaging study and the final diagnosis was 11 weeks (0–12 weeks). The most frequently observed imaging findings suggestive of malignant disease in patients with sarcomas of the pulmonary arteries were a large filling defect with vascular distension, unilaterality and a lack of improvement despite effective anticoagulation. In patients with aortic sarcomas we most frequently observed a pedunculated appearance and an atypical location of the filling defect. The F-18 FDG PET(/CT) examinations demonstrated an unequivocal hypermetabolism of the lesion in all cases (4/4). MRI proved lesion vascularization in 5/6 cases.ConclusionIntravascular unilateral or atypically located filling defects of the great vessels with vascular distension, a pedunculated shape and lack of improvement despite effective anticoagulation are suspicious for primary sarcoma on MDCT or MRI. MR perfusion techniques can add information on the nature of the lesion but the findings may be subtle and equivocal. F-18 FDG PET/CT may have a potential role in these patients and may be considered as part of the imaging workup.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Imaging features of primary Sarcomas of the great vessels in CT, MRI and PET/CT: a single-center experience

et al. 2013

View full text Add to dashboard Cite

show abstract

“…[8] FDG-PET may be useful in differentiating pulmonary thromboembolism and PAS, as blood thrombi do not take up 18 F-FDG, whereas a malignant tumor, such as PAS and does. [9] However, some reports indicate that PASs may not always show high FDG uptake. [10] Lung metastases occur in 50% and distance organs in 16%, including kidney, lymph nodes, brain, and skin, often detected at the time of diagnosis.…”

Section: Discussionmentioning

confidence: 99%

Pulmonary Artery Sarcoma - Multimodality Imaging

Jeong

Seol

Kim

et al. 2016

Journal of Clinical Imaging Science

View full text Add to dashboard Cite

show abstract

“…F-18 fluorodeoxyglucose (FDG) PET/CT is useful in identifying a pulmonary artery lesion as malignant if the luminal lesion has high FDG uptake [33] and is useful in preoperative evaluation [34]. It is also very useful in identifying active vasculitis in patients with pulmonary vasculitis such as Takayasu’s arteritis [35] and monitoring response to immunosuppressive treatment [36].…”

Section: Acquisition Protocolsmentioning

confidence: 99%

Looking beyond the thrombus: essentials of pulmonary artery imaging on CT

et al. 2014

View full text Add to dashboard Cite

BackgroundPulmonary arteries are not just affected by thrombus. Congenital and acquired conditions can also involve the pulmonary arteries. An awareness of these conditions is important for the radiologist interpreting chest computed tomography (CT).MethodsThe anatomy of the pulmonary arteries was reviewed. CT and magnetic resonance (MR) acquisition protocols for imaging the pulmonary arteries were discussed. The imaging appearances of congenital and acquired anomalies involving the pulmonary arteries, using CT and other modalities, were presented.ResultsImaging features of congenital anomalies presented include pulmonary agenesis, partial pulmonary artery agenesis, patent ductus arteriosus, pulmonary artery sling, congenital pulmonary artery stenosis and coronary to pulmonary artery fistula. Acquired pulmonary artery anomalies discussed include arteritis, infected aneurysm and sarcoma. Pulmonary artery filling defects besides thromboembolism are also discussed, including foreign body emboli. Imaging features of bronchogenic carcinoma and mediastinal fibrosis demonstrating compression of the pulmonary arteries are presented, followed by a brief discussion of post repair appearance of the pulmonary arteries for congenital heart disease.ConclusionsCongenital and acquired pulmonary artery anomalies have a characteristic appearance on a variety of imaging modalities. An acquaintance with the imaging features of these anomalies is needed to avoid misinterpretation and reach the correct diagnosis.Teaching Points• Discuss a variety of congenital and acquired anomalies of the pulmonary arteries.• Discuss the imaging appearance of the presented congenital or acquired pulmonary artery anomalies.• Describe CT and MR acquisition protocols for imaging the pulmonary arteries.• Review the anatomy of the pulmonary arteries.

show abstract

FDG-PET in diagnostic work-up of pulmonary artery sarcomas

Cited by 31 publications

References 10 publications

Imaging features of primary Sarcomas of the great vessels in CT, MRI and PET/CT: a single-center experience

Imaging features of primary Sarcomas of the great vessels in CT, MRI and PET/CT: a single-center experience

Pulmonary Artery Sarcoma - Multimodality Imaging

Looking beyond the thrombus: essentials of pulmonary artery imaging on CT

Contact Info

Product

Resources

About