The time-dependent sandwiched flow of immiscible fluids plays a vital role in petroleum extraction, biofluid mechanics, blood rheology, and so forth. Owing to their applications, the present study focuses on exploring the unsteady flow of Casson fluid through porous media sandwiched between Newtonian fluids in the channel. The channel is placed in the horizontal position, wherein the Casson fluid layer is in the central region, and Newtonian fluids are in the upperand lower regions. The governing system of equations is numerically solved using the finite difference method to obtain flow and heat transfer profiles. The influence of vital parameters on flow and heat transfer is discussed. Furthermore, the parameters of engineering interest, that is, fluid flow rate, skin friction, and Nusselt number are also analyzed in this study.