2023
DOI: 10.3390/pharmaceutics15061599
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Fe-Based Metal Organic Frameworks (Fe-MOFs) for Bio-Related Applications

Abstract: Metal–organic frameworks (MOFs) are porous materials composed of metal ions and organic ligands. Due to their large surface area, easy modification, and good biocompatibility, MOFs are often used in bio-related fields. Fe-based metal–organic frameworks (Fe-MOFs), as important types of MOF, are favored by biomedical researchers for their advantages, such as low toxicity, good stability, high drug-loading capacity, and flexible structure. Fe-MOFs are diverse and widely used. Many new Fe-MOFs have appeared in rec… Show more

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Cited by 20 publications
(3 citation statements)
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“…Metal materials are limited in practical applications due to their high bulk density, poor flexibility, and easy corrosion [ 9 , 10 , 11 , 12 ]. Lumnitzer et al [ 13 ] proposed measures to mitigate indoor electromagnetic fields by investigating the impact of metal materials on electromagnetic shielding efficiency.…”
Section: Introductionmentioning
confidence: 99%
“…Metal materials are limited in practical applications due to their high bulk density, poor flexibility, and easy corrosion [ 9 , 10 , 11 , 12 ]. Lumnitzer et al [ 13 ] proposed measures to mitigate indoor electromagnetic fields by investigating the impact of metal materials on electromagnetic shielding efficiency.…”
Section: Introductionmentioning
confidence: 99%
“…Iron (Fe) has demonstrated exceptional performance in numerous biomedical applications and is considered a promising candidate due to its chemical stability, biocompatibility, and resistance to corrosion [ 27 ]. Additionally, it is involved in bone metabolism, particularly in the processes of osteoblastic differentiation, proliferation, and calcification [ 28 ]. Furthermore, recent research investigates the use of iron nanoparticles in cancer treatment, exploiting their magnetic properties for targeted drug delivery and hyperthermia treatment [ 29 ].…”
Section: Introductionmentioning
confidence: 99%
“…Among these, Fe-MOFs have attracted substantial interest due to their potential applications in catalysis. This fascination arises from the cost-effectiveness, low toxicity, variable valence, biocompatibility, and environmental friendliness associated with the iron (Fe) element [33][34][35]. Fe-MOFs not only inherit several characteristics from conventional MOF materials, such as a large pore volume and a high specific surface area, but they also possess abundant Lewis acid centers, Brønsted acid centers, and unsaturated metal sites, rendering them ideal catalytic active centers [36].…”
Section: Introductionmentioning
confidence: 99%