Fe(III) @g-C3N4 nanocomposite-catalyzed green synthesis of di-indolyloxindole derivatives

Chemistry of trisindolines: natural occurrence, synthesis and bioactivity

“…Nanocomposite materials possess large surface areas and unique properties when compared to free nanomaterials. These materials consist of a matrix (graphene or graphene-like) and fillers, which can be metals, metal oxides, etc 99 . Haghighi and Nikoofar (2014) employed nanocomposite TiO 2 -impregnated SiO 2 as a Lewis acid to catalyze the synthesis of a series of symmetrical trisindolines under neat conditions at 50 °C for 15–120 minutes, producing the corresponding products 3, 5, 15, 17, 18, 22–25, 27 and 28 in 72–93% yields.…”

“…It is noted that among a dozen other g-C 3 N 4 -based catalysts, Fe( iii )@g-C 3 N 4 furnished the highest yield of trisindolines. 99 …”