Fear and fertility in inflammatory bowel disease: A mismatch of perception and reality affects family planning decisions

Mountifield, Réme; Bampton, Peter A.; Prosser, Ruth; Muller, Kate; Andrews, Jane M.

doi:10.1002/ibd.20839

Cited by 218 publications

(200 citation statements)

References 30 publications

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“…How well this message has been communicated to patients, and to what extent the advice is acted upon has however been little studied. Previous research conducted in Australia showed that women with IBD were fearful of the effects of medication upon pregnancy with 30% specifically fearing congenital anomalies 38 and as many as 84% fearing some adverse effect upon the pregnancy 14 . We also have data from Denmark where studies in UC and CD have demonstrated that not only do women with IBD fear the effects of their medications, but this also leads to reduced adherence 20,21 .…”

Section: Interpretation In the Context Of Previous Literaturementioning

confidence: 99%

Limited Risks of Major Congenital Anomalies in Children of Mothers With IBD and Effects of Medications

et al. 2014

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Section: Interpretation In the Context Of Previous Literaturementioning

confidence: 99%

Limited Risks of Major Congenital Anomalies in Children of Mothers With IBD and Effects of Medications

et al. 2014

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“…Women with IBD are more likely to seek information about contraception and reproductive health from their gastroenterologist than from a family care physician, although most of this counseling is initiated by patients [24]. Yet most patients seeing a gastroenterologist have no documented reproductive counseling and 41% of general practitioners report that they never raise the issue of family planning with their IBD patients [12].…”

Section: Discussionmentioning

confidence: 99%

Reproductive Health and Medication Concerns for Patients With Inflammatory Bowel Disease: Thematic and Quantitative Analysis Using Social Listening (Preprint)

Keller¹,

Mosadeghi²,

Cohen³

et al. 2018

Preprint

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Background: Inflammatory bowel disease (IBD) affects many patients of reproductive age. Most IBD medications are safe to use during pregnancy and breastfeeding, but despite this, observational studies note that women, particularly those with Crohn's Disease, have higher rates of voluntary childlessness due to concerns surrounding medication side effects, passing the disease to their offspring, fear of infertility and advice given by treating physician. Moreover, many women perceive medications to be unsafe during pregnancy. We employ social listening of online forums and social media to explore how patients with IBD understand, discuss, and act on the perceived risks and benefits associated with taking IBD medications during pregnancy and breastfeeding. Objective: The objective of this study was to gain a more thorough understanding of how individuals taking IBD medications during key reproductive periods make decisions about their medications to inform clinical practice. Having a better understanding about why patients stop or refuse to take certain medications during key reproductive periods may allow clinicians to address specific beliefs and attitudes during office visits.

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“…Dyspareunia (painful sexual congress) often occurs secondary to pelvic surgery, from IBD-associated inflammation, or psychological stress associated with IBD. Interestingly, the main cause of decreased rates of fertility in CD patients with history of previous surgeries was found to be a conscious and concerted decision against conception [17] . For women with inactive IBD and without history of pelvic surgery, fertility is however comparable to their respective age-matched peers [18] .…”

Section: Fertilitymentioning

confidence: 99%

Pregnancy and inflammatory bowel diseases: Current perspectives, risks and patient management

Hosseini‐Carroll¹,

Mutyala²,

Seth³

et al. 2015

WJGPT

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Manas K made critical revisions of the manuscript; Becker F and Alexander JS contributed equally as senior authors. Conflict-of-interest statement:There are no known conflicts of interest. The authors (Pegah Hosseini-Carroll, Monica Mutyala, Abhishek Seth, Shaheen Nageeb, Demiana Soliman, Moheb Boktor, Ankur Sheth, Jonathon Chapman, James Morris, Paul Jordan, Kenneth Manas, Felix Becker, and J Steven Alexander) have no relevant financial considerations related to this proposal, and the study was not supported by any corporate entity. There is no known intellectual property associated with this report. AbstractInflammatory bowel diseases (IBD) are chronic idiopathic inflammatory conditions characterized by relapsing and remitting episodes of inflammation which can affect several different regions of the gastrointestinal tract, but also shows extra-intestinal manifestations. IBD is most frequently diagnosed during peak female reproductive years, with 25% of women with IBD conceiving after their diagnosis. While IBD therapy has improved dramatically with enhanced surveillance and more abundant and powerful treatment options, IBD disease can have important effects on pregnancy and presents several challenges for maintaining optimal outcomes for mothers with IBD and the developing fetus/neonate. Women with IBD, the medical team treating them (both gastroenterologists and obstetricians/gynecologists) must often make highly complicated choices regarding conception, pregnancy, and post-natal care (particularly breastfeeding) related to their choice of treatment options at different phases of pregnancy as well as post-partum. This current review discusses current concerns and recommendations for pregnancy during 157November 6, 2015|Volume 6|Issue 4| WJGPT|www.wjgnet.com Hosseini-Carroll P et al . Pregnancy and inflammatory bowel diseases IBD and is intended for gastroenterologists, general practitioners and IBD patients intending to become, (or already) pregnant, and their families. We have addressed patterns of IBD inheritance, effects of IBD on fertility and conception (in both men and women), the effects of IBD disease activity on maintenance of pregnancy and outcomes, risks of diagnostic procedures during pregnancy and potential risks and complications associated with different classes of IBD therapeutics. We also have evaluated the clinical experience using "top-down" care with biologics, which is currently the standard care at our institution. Post-partum care and breastfeeding recommendations are also addressed. Core tip: Inflammatory bowel diseases (IBD) are chronic inflammatory conditions characterized by relapsing and remitting episodes of intestinal inflammation. IBD is most frequently diagnosed during peak female reproductive years, with 25% of women with IBD conceiving after their diagnosis. While therapies have improved dramatically, IBDs have important effects on pregnancy and present challenges for maintaining optimal outcomes for mothers and their developing fetus/ neonate. Women with IBD and physician...

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Fear and fertility in inflammatory bowel disease: A mismatch of perception and reality affects family planning decisions

Cited by 218 publications

References 30 publications

Limited Risks of Major Congenital Anomalies in Children of Mothers With IBD and Effects of Medications

Limited Risks of Major Congenital Anomalies in Children of Mothers With IBD and Effects of Medications

Reproductive Health and Medication Concerns for Patients With Inflammatory Bowel Disease: Thematic and Quantitative Analysis Using Social Listening (Preprint)

Pregnancy and inflammatory bowel diseases: Current perspectives, risks and patient management

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