Fears, sexual disturbances and personality features in men with prostatitis: a population‐based cross‐sectional study in Finland

Abstract

Objective To determine the occurrence of mental distress related to prostatitis in Finnish men. Subjects and methods A population-based cross-sectional survey was conducted of 2500 men aged 20±59 years living in the two northernmost provinces of Finland (Oulu and Lapland). The ®nal response rate was 75% (1832 men). Results The fear of undetected prostate cancer was reported by 17% of the men in the population who had had prostatitis, a value signi®cantly higher (P<0.001) than in healthy men. Fears of having a sexually transmitted disease and suicidal thinking were also slightly more common. The men who had had prostatitis preferred to be alone in a public toilet during voiding (58% vs 44%, P<0.001). Erectile dysfunction was reported by 43% of the men with symptomatic prostatitis and decreased libido by 24%. Self-assessment of personality, adjusted for age, showed that the men with prostatitis were more often busy and nervous than the healthy controls (P<0.001), and that they had a more meticulous attitude to life and its problems. Marital dif®culties were reported by 17% of the men who had had prostatitis at some point in their lives, and 4% were convinced that their illness had caused their divorce. Socio-economic status and social well-being had no apparent in¯uence on the occurrence of prostatitis. Conclusions This survey showed that psychological stress is common in men with prostatitis. Urologists and general practitioners should consider that a consultation with a psychiatrist may be appropriate for selected men with prostatitis.

Assessment of Perigenital Sensitivity and Prostatic Mast Cell Activation in a Mouse Model of Neonatal Maternal Separation

“…Second, the behavioral and molecular changes resulting from NMS are largely due to dysregulation of the HPA axis [15][16][17][18] , suggesting that the effect is centrally-mediated and could have comorbid results, including changes in anxiety-and/or depression-like behaviors and increased sensitivity in other pelvic organs or more distant locations. This comorbid phenotype is indicative of what is commonly seen clinically and may be more representative of CP/CPPS patients as a whole 5,[28][29][30][31]42 . Third, based on these changes occurring as a result of HPA axis dysregulation, the impact of stress should be of utmost concern during both the NMS procedure and later behavioral testing and in vitro analysis.…”

“…Patients with CP/CPPS report pain in the perineum, rectum, prostate, penis, testicles, and/or abdomen 28 , experience a higher degree of psychological stress than control patients 29 , and commonly present with symptoms of or are diagnosed with comorbid chronic pelvic pain or mood disorders 5,[29][30][31] . Recurrent infection, leaky epithelium, neurogenic inflammation, and autoimmunity have all been surmised as potential underlying causes of CP/CPPS 2,32,33 , as well as mast cell activation and degranulation 34 .…”

Fluoroquinolone–macrolide combination therapy for chronic bacterial prostatitis: retrospective analysis of pathogen eradication rates, inflammatory findings and sexual dysfunction

“…[50][51][52][53][54] Sexual dysfunction may manifest as ED, orgasmic/ejaculatory dysfunction or altered libido, and has a deleterious effect on the relationship of prostatitis patients. [55][56][57] Moreover, a significantly higher impact of chronic prostatitis/chronic pelvic pain syndrome on the quality of life (NIH-CPSI domain 3) has been demonstrated in patients with sexual dysfunction when compared to patients with normal sexual function.…”

Chronic Prostatitis/Chronic Pelvic Pain Syndrome and Male Bladder Pain Syndrome/Interstitial Cystitis: How Are They Related?

“…The clinical domains of UPOINT are Urinary symptoms, Psychosocial dysfunction, Organ-specific findings, Infection, Neurologic/systemic conditions, and Tenderness of muscles, providing mnemonic UPOINT. With sexual dysfunction affecting 40-70% of all men with CP/CPPS [39][40][41], the inclusion of an additional domain for sexual dysfunction was proposed, and a modified UPOINT algorithm (UPOINTs) has been suggested [42][43][44].…”