Feasibility and efficacy of a new non-invasive surface cooling device in post-resuscitation intensive care medicine

Haugk, Moritz; Sterz, Fritz; Grassberger, Martin; Uray, Thomas; Kliegel, Andreas; Janata, Andreas; Richling, Nina; Herkner, Harald; Laggner, Anton N.

doi:10.1016/j.resuscitation.2007.03.001

Cited by 124 publications

(46 citation statements)

References 10 publications

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“…In recent years, several invasive 6,7,22-24 as well as noninvasive 2,3,5,7,13,[24][25][26][27][28] cooling techniques for induction of mild hypothermia were investigated in patients after cardiac arrest. The cooling rate of these devices ranged from 0.25 to 1.2°C ⁄ hour.…”

Section: Discussionmentioning

confidence: 99%

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Surface Cooling for Rapid Induction of Mild Hypothermia After Cardiac Arrest: Design Determines Efficacy

Uray

Haugk

Sterz

et al. 2010

Academic Emergency Medicine

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Objectives: Recently, a novel cooling pad was developed for rapid induction of mild hypothermia after cardiac arrest. The aim of this study was to evaluate the cooling efficacy of three different pad designs for in-hospital cooling.Methods: Included in this prospective interventional study were patients with esophageal temperature (Tes) > 34°C on admission. The cooling pad consists of multiple cooling units, filled with a combination of graphite and water, which is precooled to -18°C (design A) or to -9°C (designs B and C) before use. The designs of the cooling pad differed in number, shape, and thickness of the cooling units, with weights of 9.7 kg (design A), 5.3 kg (design B), and 6.2 kg (design C). All three designs were tested in sequential order and were changed according to the results found in the previous trial. Cooling was started after admission until Tes = 34°C, when the cooling pad was removed. The target temperature of Tes = 32-34°C was maintained for 24 hours. Data are presented as medians and interquartile ranges (IQRs = 25%-75%) or proportions.Results: Cooling rates were 3.4°C ⁄ hour (IQR = 2.5-3.7) with design A (n = 12), 2.8°C ⁄ hour (IQR = 1.6-3.3) with design B (n = 7), and 2.9°C ⁄ hour (IQR = 1.9-3.6) with design C (n = 10; p = 0.5). To reach 34°C, the cooling pad had to be exchanged with a new one due to melting and therefore depleting cooling capacity in three patients with design A, in five patients with design B, and in no patient with design C (p = 0.004). Conclusions:With adequate design and storage temperature, the cooling pad proved to be efficient for rapid in-hospital cooling of patients resuscitated from cardiac arrest.

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Section: Discussionmentioning

confidence: 99%

“…In contrast to other cooling devices with automatic temperature feedback control, 6,22,28 the use of the cooling pad requires temperature management. In a recent study, cooling with ice packs and conventional cooling blankets resulted in unintentional overcooling in the majority of patients.…”

Section: Discussionmentioning

confidence: 99%

Surface Cooling for Rapid Induction of Mild Hypothermia After Cardiac Arrest: Design Determines Efficacy

Uray

Haugk

Sterz

et al. 2010

Academic Emergency Medicine

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“…Disadvantages include expense, possible skin sloughing, and slower cooling rates in very obese people. [72,74] A promising technology is the Thermosuit System (Life Recovery Systems, Kinnelon, NJ, USA), which surrounds patients directly with cool water and also possesses a feedback control mechanism. Animal studies suggest that it provides a cooling rate of 9.7°C per hour in 30-kg pigs, versus 3.0°C per hour in humans.…”

Section: Surface Coolingmentioning

confidence: 99%

Therapeutic Hypothermia for Cardiac Arrest

Sadaka¹

2013

Therapeutic Hypothermia in Brain Injury

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“…Therapeutic hypothermia is easily and rapidly inducible even in the prehospital setting using either infusion of LVICF (Kliegel et al 2007) or external cooling methods and maintained in the ICU either externally (Haugk et al 2007) or using special endovascular cooling systems (Pichon et al 2007). There is however, a growing body of evidence suggesting that the protective effects of mild hypothermia should be pursued already during CPR and prior to the reperfusion injury occurring after ROSC Nozari et al 2004;Nozari et al 2006).…”

Section: Timing Of Hypothermiamentioning

confidence: 99%

“…It is speculative whether the exclusion from the treatment serves as a self-fulfilling prophecy of presumed futility. Prehospital cooling alone is likely to be insufficient from the therapeutic viewpoint -the cold chain needs to be kept unbroken by maintaining hypothermia in the ICU (Kliegel et al 2007) in order to provide optimal hypothermic cerebral protection. This mandates that indications to initiate prehospital cooling are similar to those of the receiving hospital for induction of therapeutic hypothermia.…”

Section: Cooling After Return Of Spontaneous Circulationmentioning

confidence: 99%

Pre‐hospital cardiac arrest and induction of mild hypothermia: studies on epidemiology and feasibility

Kämäräinen¹

2010

Acta Anaesthesiol Scand

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Feasibility and efficacy of a new non-invasive surface cooling device in post-resuscitation intensive care medicine

Cited by 124 publications

References 10 publications

Surface Cooling for Rapid Induction of Mild Hypothermia After Cardiac Arrest: Design Determines Efficacy

Surface Cooling for Rapid Induction of Mild Hypothermia After Cardiac Arrest: Design Determines Efficacy

Therapeutic Hypothermia for Cardiac Arrest

Pre‐hospital cardiac arrest and induction of mild hypothermia: studies on epidemiology and feasibility

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