Feasibility and yield of a new EUS histology needle: results from a multicenter, pooled, cohort study

Iglesias‐García, Julio; Poley, Jan Werner; Larghi, Alberto; Giovannini, Marc; Petrone, Maria Chiara; Abdulkader, Ihab; Monges, Geneviève; Costamagna, Guido; Arcidiacono, Paolo Giorgio; Biermann, Katharina; Rindi, Guido; Bories, Erwan; Dogloni, Claudio; Bruno, Marco J.; Domínguez–Muñoz, J. Enrique

doi:10.1016/j.gie.2011.01.053

Cited by 285 publications

(339 citation statements)

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“…without a real core or when the core was fragmented and difficult to be evaluated); grade 4 -excellent sample, suitable for histological evaluation, providing tissue architecture of the target lesion (i.e. with a real core) (38,39). The percentage of cases in which the pathologist was able to perform an immunohistochemical analysis was also evaluated as secondary outcome.…”

Section: Variables Evaluatedmentioning

confidence: 99%

“…Nowadays a new 19-gauge fine needle biopsy needle (ProCore TM , Cook Endoscopy Inc., Limerick, Ireland) device has been designed. Feasibility, yield and high diagnostic accuracy of this needle have been recently report in a large series of consecutive patients in a multicenter study, but different methodologies were used in each center (39). Aim of the present study was to evaluate the diagnostic accuracy of this newly developed 19-gauge histology needle in a single center using a homogeneous methodology.…”

Section: Introductionmentioning

confidence: 96%

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Evaluation of the adequacy and diagnostic accuracy of the histology samples obtained with a newly designed 19-gauge EUS histology needle

Iglesias‐García

Abdulkader

Lariño‐Noia

et al. 2014

Rev. esp. enferm. dig.

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Background: Endoscopic ultrasound (EUS)-guided fine needle aspiration (FNA) is an accurate technique for sampling intraintestinal and extraintestinal lesions. However, cytology possesses certain limitations, which may be overcome if histological specimens are provided to the pathologist.Aim: The aim of the study was to evaluate the accuracy of a newly developed 19G histology needle.Methods: Retrospective analysis of a prospectively collected data base including patients who underwent EUS-guided biopsy with the 19G ProCore TM histology needle for the evaluation of intraintestinal or extraintestinal lesions. Samples were obtained after one needle pass, recovered into ThinPrep ® and processed for histological analysis. Results were compared to the gold standard of surgical histopathology, or global pathological, clinical and radiological assessment, and follow-up in non-operated cases. Results are shown as mean ± SD. Percentage of optimal samples for histological evaluation and the overall diagnostic accuracy were evaluated.Results: 87 patients (mean age 62.9 years, range 25-88 years, 36 woman) were included. Lesions mean size was 41.6 ± 21.3 mm. 66 lesions (75.9 %) were considered as malignant and 21 (24.1 %) as benign. EUS-guided biopsy was feasible in all cases (100 %). Sample quality was adequate for histological assessment in 82 lesions (94.2 %). In the remaining cases the sample was adequate for cell-block evaluation. Sensitivity, specificity, PPV, NPV, and overall accuracy for malignancy were 93.4 %, 100 %, 100 %, 84 %, and 95.4 %, respectively. There were no complications related to the procedure. Conclusion:The EUS-guided biopsy with the 19G histology needle provides with an optimal core sample for histological evaluation allowing a high histopathologic diagnostic accuracy.

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Section: Variables Evaluatedmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 96%

Evaluation of the adequacy and diagnostic accuracy of the histology samples obtained with a newly designed 19-gauge EUS histology needle

Iglesias‐García

Abdulkader

Lariño‐Noia

et al. 2014

Rev. esp. enferm. dig.

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“…Patients who were randomized to EUS-FNB had significantly higher diagnostic yield compared to patients who underwent EUS-FNA (75 % vs. 20 %, P = 0.010) [28]. Previously published prospective studies have also noted high diagnostic accuracy of the FNB technique in non-pancreatic mass lesions [23,35]. A recent study evaluated 125 patients with nonpancreatic masses using the 22-G core biopsy needle.…”

Section: Discussionmentioning

confidence: 99%

“…More recently, a new generation of core biopsy needles have been introduced (Echotip Procore TM , Cook Medical, Winston-Salem, NC). Multiple prospective cohort studies have suggested a significant improvement in diagnostic yield with EUS-FNB, while one RCT and some retrospective series have shown varying results [19,22,23]. To date, there is limited published data comparing EUS-FNA and EUS-FNB with regard to diagnostic yield in pancreatic and non-pancreatic Background and study aims: Techniques to optimize endoscopic ultrasound-guided tissue acquisition (EUS-TA) in a variety of lesion types have not yet been established.…”

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confidence: 99%

Untitled

2016

Endosc Int Open

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“…Most importantly, its diagnostic yield is strongly limited for lesions located in pancreatic head due to mechanical friction of the needle firing mechanism ensuing from the bended scope position (49)(50)(51)(52). In this setting a novel needle have been designed (Procore TM histology needle) to overcome trucut needle limitations (mainly in the second portion of the duodenum) and initial preliminary results are promising and it appears that may help solve this problem, allowing a histological evaluation with an overall accuracy of 85.9% (89.4% in pancreatic solid lesions) (53). There are also other needles in the market (Olympus EZShot2 NA-230H-8022), designed to obtain histological samples, but its clinical usefulness and safety are still under evaluation.…”

Section: Introductionmentioning

confidence: 99%

The role of endoscopic ultrasound (EUS) in relation to other imaging modalities in the differential diagnosis between mass forming chronic pancreatitis, autoimmune pancreatitis and ductal pancreatic adenocarcinoma

Iglesias‐García

Lindkvist

Lariño‐Noia³

et al. 2012

Rev. esp. enferm. dig.

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Differential diagnosis of solid pancreatic lesions remains as an important clinical challenge, mainly for the differentiation between mass forming chronic pancreatitis, autoimmune pancreatitis and pancreatic adenocarcinoma. Endoscopic ultrasound (EUS), computed tomography (CT) and magnetic resonance imaging (MRI) can all provide valuable and complementary information in this setting. Among them, EUS has the unique ability to obtain specimens for histopathological diagnosis and can therefore play a crucial role in the evaluation patients with inconclusive findings on initial examinations. Nowadays, new developed techniques associated to EUS, like elastography and contrast enhancement, have shown promising results for the differential diagnosis of these pancreatic lesions.Key words: Endoscopic ultrasound. CT scan. MRI. Pancreatic tumors. INTRODUCTIONDifferential diagnosis of solid pancreatic masses remains a challenge, despite recent advances in different diagnostic procedures. In this article, the role of endoscopic ultrasound (EUS) including EUS-guided FNA, elastography and contrast enhancement will be reviewed in relation to computer tomography (CT), magnetic resonance tomography (MRI) and magnetic resonance cholangiopancreatography (MRCP). Differential diagnosis between malignant lesions and mass-forming chronic pancreatitis or focal autoimmune pancreatitis will be discussed. Tumor staging and evaluation of resectability of these pancreatic lesions will not be evaluated. Other imaging techniques, like PET-scan or octreoscan will not be analyze, because their usefulness in this context is unclear.Differential diagnosis between malignant pancreatic lesions (pancreatic cancer, pancreatic metastasis) and massforming chronic pancreatitis CT scan is the most widely spread imaging modality for evaluation of pancreatic solid masses and considered as the most comprehensive tool for diagnosis and surgical staging of pancreatic malignancies (1). CT technology has significantly advanced over the last years, multidetector helical CT scan allows for very thin sliced cuts, providing a higher image resolution and faster image acquisition (Fig. 1) Vol. 104. N.° 6, pp. 315-321, 2012 Disclosures: Dr. Julio Iglesias-García is international advisor of Cook-Medical. Dr. J. Enrique Domínguez-Muñoz is international advisor of Pentax Medical Company.Received: 27-03-201227-03- Accepted: 20-04-2012 Correspondence: Julio Iglesias-García. Department of Gastroenterology.

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Feasibility and yield of a new EUS histology needle: results from a multicenter, pooled, cohort study

Cited by 285 publications

References 45 publications

Evaluation of the adequacy and diagnostic accuracy of the histology samples obtained with a newly designed 19-gauge EUS histology needle

Evaluation of the adequacy and diagnostic accuracy of the histology samples obtained with a newly designed 19-gauge EUS histology needle

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The role of endoscopic ultrasound (EUS) in relation to other imaging modalities in the differential diagnosis between mass forming chronic pancreatitis, autoimmune pancreatitis and ductal pancreatic adenocarcinoma

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