Feasibility of a Compact Fiberoptic Probe for Real Time Tracing of Subsurface Skin Birefringence

Tugbaev, V. A.; Myllylä, Risto; Mashchenko, A. I.

doi:10.1364/ecbo.2005.mf4

Cited by 3 publications

(4 citation statements)

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“…As described in Fig. 1(b), either of these components the readout interferometer compensates optical path length differences in the sensing interferometer within a given interval of depth in the sample, and evolves spatial fringes which are read out by optoelectronic means without any mechanical scanning in depth [4].…”

Section: Experiments and Resultsmentioning

confidence: 99%

Novel OCT system based on a tandem interferometer

Eom

Tougbaev

et al. 2007

2007 Conference on Lasers and Electro-Optics - Pacific Rim

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Section: Experiments and Resultsmentioning

confidence: 99%

Novel OCT system based on a tandem interferometer

Eom

Tougbaev

et al. 2007

2007 Conference on Lasers and Electro-Optics - Pacific Rim

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“…In some practical cases, the zero-order interference fringe should be shifted from the center of the WP aperture. For that, it is necessary to change the relative thicknesses of the wedges 12 or insert in front or behind WP, a birefringent plate, which is cheaper. 23 At the design stage, a required position of L can be present beneath the sample surface by choosing the proper plate thickness.…”

Section: Basic Principlementioning

confidence: 99%

“…Before now, we made just speculative attacks on this challenge. 12,13 Here, we reveal the basic principle and consider in more detail the experimental verification of the specific solution proposed for such systems as well as mention the simplified algorithm for mapping birefringence of dermis through measurements of the depolarization ratio. 14…”

Section: Introductionmentioning

confidence: 99%

Quasi-holographic solution to polarization-sensitive optical coherence tomography acceptable to nonlaboratory applications

Tougbaev

Eom

et al. 2008

J. Biomed. Opt.

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Experimental proof-of-concept is presented for a quasi-holographic solution to polarization-sensitive optical coherence tomography (PS OCT). Due to decoupling between the reference and sample beams by polarization, the solution seems acceptable to acquisition and communication of optical data in the nonlaboratory environment. The nonlab environment implies uncontrollable disturbances, e.g., temperature changes and mechanical effects happening under shop testing in industry or routine examinations in common clinics and hospitals. For mapping the collagen-related depolarization ratio of light backscattered from the human dermis, a phenomenological model is evolved from the theory of light depolarization in crystalline polymers. The model yielded a simplified intensity-based estimation algorithm. The design concept and the model rely on a submillimeter tumor thickness as a proofed prognostic factor and an important criterion for complementary functional diagnostics of skin cancers in their early phase. Choice of the model is inspired by similarity of structural and optical properties between liquid-crystal collagen fibers in the dermis and birefringent crystalline lamellae in some polymer materials. The model gives a plausible interpretation of a peculiarity of cumulative birefringence in the abnormal skin dermis. Following a top-down approach to design, the authors attempt to contribute to bridging the gap between practitioners' concerns and academic studies.

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“…Seemingly, the first attempt to embody the aforesaid concept in a PS OCT system has been undertaken recently 20 . The "proof-of-concept" was outlined for the system which is, in fact, a tandem of the sensing Michelson interferometer with the fixed reference mirror and the readout interferometer based on Wollaston prism of special design.…”

Section: Qualitative Theorymentioning

confidence: 99%

<title>Polarization sensitive optical coherence tomography for application conditions with external perturbations</title>

et al. 2007

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A challenge is accepted to identify depth resolved optical birefringence of turbid media, particularly human skin using polarization sensitive optical coherence tomography under external environmental perturbations, e.g. under application conditions in clinics and hospitals. A novel concept is advanced and respective design is elaborated for a system which comprises a source of low-coherence light, a tandem of a readout interferometer and a sensing interferometer with reference and sample arms, and a handheld probe integrated into the sensing interferometer through polarization-maintaining fibers.The system provides fast electro-optic switching over orthogonal polarization components of a measurand light beam at the same output from the sensing interferometer. At said output either of the aforementioned components remains perpendicular to the polarization plane of light in the reference arm. For either of the components the readout interferometer compensates optical path length differences in the sensing interferometer within a given interval of depth in the sample, and evolves spatial fringes which are read out by optoelectronic means without any mechanical scanning in depth. The fringes are devoid of cross-correlation artifacts inasmuch as the readout interferometer recombines coherently the measurand beam and the reference beam having mutually orthogonal polarizations only.

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Feasibility of a Compact Fiberoptic Probe for Real Time Tracing of Subsurface Skin Birefringence

Cited by 3 publications

References 0 publications

Novel OCT system based on a tandem interferometer

Novel OCT system based on a tandem interferometer

Quasi-holographic solution to polarization-sensitive optical coherence tomography acceptable to nonlaboratory applications

<title>Polarization sensitive optical coherence tomography for application conditions with external perturbations</title>

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