Feasibility of delivering HPV vaccine to girls aged 10 to 15 years in Uganda

Mugisha, Emmanuel; LaMontagne, D. Scott; Ar, Katahoire; Murokora, Dan; Kumakech, Edward; Seruyange, R; Tsu, V.

doi:10.4314/ahs.v15i1.5

Cited by 38 publications

(43 citation statements)

References 15 publications

(20 reference statements)

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“…A mentionable number of participants had not yet had sexual intercourse (20%) in this cohort. Similar studies about HPV vaccine acceptability have also shown that a number of AYA had not yet engaged in sexual activity and therefore were still ideal candidates to receive the HPV vaccine Mugisha et al, 2015). Findings from this study demonstrate favourable acceptability towards the HPV vaccine among a population who are at the highest risk of developing HPV related cancers and unable to afford the vaccine.…”

Section: Acceptability Of the Hpv Vaccine: Selfsupporting

confidence: 59%

“…A study examining the feasibility of HPV vaccines for girls in Uganda, interviews and focus groups were conducted with key informants including health workers, teachers, and national health officials. The goal of the cross-sectional study was to better understand the most appropriate HPV vaccine (bivalent) delivery strategy for young women aged 10-15 years (Mugisha et al, 2015). Vaccine uptake and acceptability rates were reported and evaluated for two different delivery strategies in two Ugandan districts: grade-based (grade 5) and age-based (10-year-olds).…”

Section: Uptake Of the Hpv Vaccine: Low-and Middle-income Countriesmentioning

confidence: 99%

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A pivotal time in global cervical cancer prevention: Examining young women's awareness about the human papillomavirous and attitudes towards the HPV vaccine in Durban, South Africa

Russell¹

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It is a pivotal time in cervical cancer prevention for young South African (SA) women. Cervical cancer and infection with human immunodeficiency virus are both major public health concerns in SA. This study describes knowledge of female adolescents and young adults (AYA) about HPV, cervical cancer and explores predictors of HPV vaccine and HPV self-sample testing acceptability. In this cross-sectional study, questionnaires were administered to 122 female AYA who involved in a longitudinal study (AYAZAZI) which examined risk factors involved with HIV acquisition. Results indicated that although awareness and knowledge about these topics was very low among participants, as were perceptions of risk of acquiring HPV and developing cervical cancer, acceptability was very high towards HPV vaccines for self (97%) and (future) children (95%), as well for self-sample testing (85%). No significant variables were found to be associated with risk perception or self-sample acceptance. A significant difference was found between participants' perceived risk of acquiring HPV, HIV, and developing cervical cancer compared to the risk they felt other female AYA in their communities were at. The most influential sexual and reproductive health (SRH) information source and significant influences on HPV vaccine recommendations for participants were health care providers. Findings from this study are important in designing effective cervical cancer control programs that can attract more AYA for HPV vaccines and screening. As the HPV vaccine has only recently been introduced at a national level in SA, this study about awareness and vaccine acceptability is timely.

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Section: Acceptability Of the Hpv Vaccine: Selfsupporting

confidence: 59%

Section: Uptake Of the Hpv Vaccine: Low-and Middle-income Countriesmentioning

confidence: 99%

A pivotal time in global cervical cancer prevention: Examining young women's awareness about the human papillomavirous and attitudes towards the HPV vaccine in Durban, South Africa

Russell¹

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“…Vaccinations have been identified as the most common type of intervention in schools in at least 35 countries or territories [9], and there is evidence of effectiveness from primary studies regarding feasibility of school-based vaccination programs [48,49]. Yet no SRs on vaccinations fulfilled the inclusion criteria for this overview, suggesting the need for these SRs to be conducted.…”

Section: Overall Effectiveness Of School Health Servicesmentioning

confidence: 99%

Investigating the effectiveness of school health services delivered by a health provider: a systematic review of systematic reviews

Levinson

Kohl

Baltag

et al. 2019

Preprint

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24Schools are the only institution regularly reaching the majority of school-age children 25 and adolescents across the globe. Although at least 102 countries have school health services, 26 there is no rigorous, evidence-based guidance on which school health services are effective 27 42 3 48 healthy setting for living, learning and working" [1]. In 2000, WHO, the United Nations 49 Educational, Scientific and Cultural Organization (UNESCO), the United Nations Children's 50 Fund (UNICEF) and the World Bank developed a partnership for Focusing Resources on 51 Effective School Health -a FRESH Start approach [2]. The FRESH framework promotes 52 four pillars: health-related school policies, provision of safe water and sanitation, skills-based 53 health education and school-based health and nutrition services [2]. While various guidance 54 documents have been published by United Nations (UN) organizations addressing a range of 55 services from oral health to malaria [3-7], there is no internationally accepted guideline 56 regarding school health services. This systematic review of systematic reviews, henceforth 57 referred to as an overview, will inform the upcoming development of a WHO guideline that 58 addresses one pillar of the FRESH framework: school health services delivered by a health 59 provider. 60 Schools offer a unique platform for health care delivery. In 2015, the global means for 61 the primary and secondary net school enrollment rates were 90% and 65%, respectively, thus 62 the potential reach of school health services is wide [8]. Additionally, a recent review found 63 that school-based or school-linked health services already exist in at least 102 countries [9]. 64 The 2017 Global Accelerated Action for the Health of Adolescents (AA-HA!) 65 implementation guidance calls for the prioritization of school health programs as an 66 important step towards universal health coverage and urges that "Every school should be a 67 health promoting school" [10]. 68 The primary objective of this overview was to explore the effectiveness of school-69 based or school-linked health services delivered by a health provider for improving the health 70 of school-age children and adolescents. Through a comprehensive literature search, the 71 overview aimed to identify health areas and specific school health service interventions that 72 have at least some evidence of effectiveness. It was also designed to suggest further research 4 73 in areas where recent systematic reviews (SRs) exist, but with insufficient evidence. Finally, 74 the overview aimed to identify the health areas and specific school health services 75 interventions for which no SRs were found, whether because the primary literature does not 76 exist or where there are primary studies but no SR has been conducted. 77 METHODS 78This overview was conducted using the preferred reporting items for systematic 79 reviews and meta-analyses (PRISMA) [11]. A protocol was developed a priori that outlined 80 the overview objectives, aims, operational definitions, search ...

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“…21,22 To study these questions, PATH partnered with ministries of health in four low-and middle-income countries-India,Peru,Uganda,andVietnam-tocarryoutdemonstrationprograms. 23 Conductedfrom2007-2010andreachingfrom4000 to25000youngadolescentgirls,theseprogramsresultedin56%-99% three-dosevaccinecoverage,illustratedtheacceptabilityandfeasibilityofsuchprograms,estimatedthecostsofHPVvaccinedeliveryin low-resourcesettings, [23][24][25][26][27][28][29][30][31] andprovidedaguidefortheimplementation of such programs in other countries. 32 In addition, Merck & Co establishedtheGardasilAccessProgram(GAP)in2009.…”

Section: Early Pilots and National Introductionsmentioning

confidence: 99%