Feasibility of dose enhancement assessment: Preliminary results by means of Gd-infused polymer gel dosimeter and Monte Carlo study

Santibáñez, M.; Guillen, Y.; Chacón, D.; Figueroa, R.; Valente, M.

doi:10.1016/j.apradiso.2018.04.016

Cited by 12 publications

(2 citation statements)

References 24 publications

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“…The output of most gel dosimeters does not depend significantly on the radiation quality when considering high-energy photon and electron radiotherapy beams [ 7 , 88 ] due to the similar LET in the MeV energy range for these particles [ 97 ]. However, dedicated preliminary characterization is required to use gel dosimetry for applications with non-negligible LET differences compared with typical radiotherapy radiation qualities, as occurs for brachytherapy [ 98 , 99 , 100 ] and radiology [ 14 , 101 , 102 ]. In order to avoid systematic errors in the dose distribution assessment for low-energy applications, the corresponding gel dosimeter dose–response output needs to be obtained for the specific beam quality, and the relative performance to the reference quality ( 60 Co) may serve to correlate with their application in the MeV range.…”

Section: Operational Properties Of Gel Dosimetrymentioning

confidence: 99%

Chemical Overview of Gel Dosimetry Systems: A Comprehensive Review

Macchione

Páez

Strumia

et al. 2022

Gels

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Advances in radiotherapy technology during the last 25 years have significantly improved both dose conformation to tumors and the preservation of healthy tissues, achieving almost real-time feedback by means of high-precision treatments and theranostics. Owing to this, developing high-performance systems capable of coping with the challenging requirements of modern ionizing radiation is a key issue to overcome the limitations of traditional dosimeters. In this regard, a deep understanding of the physicochemical basis of gel dosimetry, as one of the most promising tools for the evaluation of 3D high-spatial-resolution dose distributions, represents the starting point for developing new and innovative systems. This review aims to contribute thorough descriptions of the chemical processes and interactions that condition gel dosimetry outputs, often phenomenologically addressed, and particularly formulations reported since 2017.

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Section: Operational Properties Of Gel Dosimetrymentioning

confidence: 99%

Chemical Overview of Gel Dosimetry Systems: A Comprehensive Review

Macchione

Páez

Strumia

et al. 2022

Gels

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“…Recently, addition of high atomic elements (such as bismuth, gadolinium, silver or gold nanoparticles, etc.) has been investigated for increasing photon sensitivity [80][81][82][83][84][85][86][87][88][89][90][91][92].…”

Section: Characterization and Performancementioning

confidence: 99%

Hydrogels for Three-Dimensional Ionizing-Radiation Dosimetry

Marrale

D’Errico

2021

Gels

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Radiation-sensitive gels are among the most recent and promising developments for radiation therapy (RT) dosimetry. RT dosimetry has the twofold goal of ensuring the quality of the treatment and the radiation protection of the patient. Benchmark dosimetry for acceptance testing and commissioning of RT systems is still based on ionization chambers. However, even the smallest chambers cannot resolve the steep dose gradients of up to 30–50% per mm generated with the most advanced techniques. While a multitude of systems based, e.g., on luminescence, silicon diodes and radiochromic materials have been developed, they do not allow the truly continuous 3D dose measurements offered by radiation-sensitive gels. The gels are tissue equivalent, so they also serve as phantoms, and their response is largely independent of radiation quality and dose rate. Some of them are infused with ferrous sulfate and rely on the radiation-induced oxidation of ferrous ions to ferric ions (Fricke-gels). Other formulations consist of monomers dispersed in a gelatinous medium (Polyacrylamide gels) and rely on radiation-induced polymerization, which creates a stable polymer structure. In both gel types, irradiation causes changes in proton relaxation rates that are proportional to locally absorbed dose and can be imaged using magnetic resonance imaging (MRI). Changes in color and/or opacification of the gels also occur upon irradiation, allowing the use of optical tomography techniques. In this work, we review both Fricke and polyacrylamide gels with emphasis on their chemical and physical properties and on their applications for radiation dosimetry.

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