“…Analyses of common ingredients of effective treatments have identified some common mechanisms such as change in negative personal meanings of the trauma and activation and change of trauma memories, which may help with making interventions more focused and possibly increasing their efficacy and efficiency further (Brown, Belli, Asnaani, & Foa, 2019;Olff et al, in press;Schnyder et al, 2015). In addition, research into innovative approaches such as pharmacological enhancers in exposure therapy (De Kleine, Rothbaum, & van Minnen, 2013) or neurofeedback (Lanius et al, 2015) There have been increased efforts to adapt and evaluate evidence-based interventions for children and adolescents (Kramer & Landolt, 2011;Nocon et al, 2017) and patients with multiple traumatic events and complex needs such as military veterans (Kitchiner, Roberts, Wilcox, & Bisson, 2012), refugees (see also section 7) (Lely et al, 2019;Nocon et al, 2017), survivors of childhood sexual abuse (Cloitre et al, 2010;Steil et al, 2018) and patients with comorbid personality disorders (Slotema, van Den Berg, Driessen, Wilhelmus, & Franken, 2019). Metaanalyses suggest that the same types of treatment, trauma-focused treatments, obtain the greatest effect sizes in most of these populations (Ehring et al, 2014;NICE, 2018).…”