Feasibility of one breath-hold cardiovascular magnetic resonance compressed sensing cine for left ventricular strain analysis

Abstract

ObjectiveTo investigate the feasibility of 3D left ventricular global and regional strain by using one breath-hold (BH) compressed sensing cine (CSC) protocol and determine the agreement between CSC and conventional cine (CC) protocols.MethodsA total of 30 volunteers were enrolled in this study. Cardiovascular magnetic resonance (CMR) images were acquired using a 1.436 T magnetic resonance imaging (MRI) system. The CSC protocols included one BH CSC and the shortest BH CSC protocols with different parameters and were only performed in short-axis (SA) view following CC protocols. Left ventricular (LV) end-diastole volume (EDV), end-systole volume (ESV), stroke volume (SV), and ejection fraction (EF) global and regional strain were calculated by CC, one BH CSC, and shortest BH CSC protocols. The intraclass correlation coefficient (ICC) and coefficient of variance (CV) of these parameters were used to determine the agreement between different acquisitions.ResultsThe agreement of all volumetric variables and EF between the CC protocol and one BH CSC protocol was excellent (ICC > 0.9). EDV, ESV, and SV between CC and shortest BH CSC protocols also had a remarkable coherence (ICC > 0.9). The agreement of 3D LV global strain assessment between CC protocol and one BH CSC protocol was good (ICC > 0.8). Most CVs of variables were also good (CV < 15%). ICCs of all variables were lower than 0.8. CVs of all parameters were higher than 15% except global longitudinal strain (GLS) between CC and shortest BH CSC protocols. The agreement of regional strain between CC and BH CSC protocols was heterogeneous (-0.2 < ICC < 0.7). Many variables of CVs were poor.ConclusionNotably, one BH CSC protocol can be used for 3D global strain analysis, along with a good correlation with the CC protocol. The regional strain should continue to be computed by the CC protocol due to poor agreement and a remarkable variation between the protocols. The shortest BH CSC protocol was insufficient to replace the CC protocol for 3D global and regional strain.

The effects of flip angle and gadolinium contrast agent on single breath-hold compressed sensing cardiac magnetic resonance cine for biventricular global strain assessment

“…This observation suggests that the CS cine, used in our study as a single breath-hold high-speed technique, may not furnish equivalent strain values for patients with various cardiovascular conditions even with almost the same acquisition parameters (see Table 1). This discovery fails to replicate the strain value comparison results observed in other studies between CS-based cine and conventional cine, which demonstrate only minor differences (23)(24)(25). The accurate functioning of the FT algorithm is heavily reliant on achieving a high contrast between the blood and myocardium (26).…”

Comparison between compressed sensing and segmented cine cardiac magnetic resonance: a meta-analysis

“…We also acknowledge our limited ability to detect possible publication bias due to the small number of studies. Lastly, CS methods have been applied to 3D cine which can provide comparable left ventricular functional and morphological assessment [ 41 ]. The current meta-analysis only examined CS application to 2D cine.…”