Feasibility of ovarian cryopreservation in borderline ovarian tumours

Abstract

In patients treated for a BOT, OC was eventually feasible in 53% of patients in whom this procedure was initially planned. In 18%, this procedure was aborted because no macroscopic healthy ovarian tissue could be found.

Ex-vivo oocyte retrieval for fertility preservation

“…This combination of ovarian tissue cryobanking with vitrification of IVM oocytes provides an alternative method of fertility preservation. The efficacy of oocyte vitrification has been confirmed and the post-thaw survival rate of 94%, implantation rate of 20.4%, and a PR of 46.7% was demonstrated (23). However, the implantation rates after IVM are still significantly below the implantation rates after IVF/ICSI (24).…”

Evaluation of ovarian and testicular tissue cryopreservation in children undergoing gonadotoxic therapies

“…Analysis of 17 patients with benign ovarian tumors who underwent ovarian tissue cryopreservation showed that surgical tumor resection could be performed with tissue preservation [15]. Studies regarding the psychological aspects of gonadal tissue harvesting in prepubertal children have also shown that the majority of patients and their families are amenable to such medical options [20,35,46].…”

Faisabilité de la congélation embryonnaire dans la préservation de la fertilité féminine

“…Dans le cas des tumeurs borderline de l'ovaire, la cryoconservation de tissu ovarien sain n'est pas toujours ré alisable en pratique [22]. Dans le cas d'une tumeur borderline ré cidivante de stade IIIa, Gallot et al avaient ré alisé une stimulation ovarienne pour FIV en urgence, avec une ponction ovocytaire ré alisé e juste avant l'ovariectomie [23].…”