Feasibility of red blood cell transfusion through small bore central venous catheters used in neonates

Wong, Edward C.C.; Schreiber, Seth; Criss, V. R.; LaFleur, Bonnie; Rais-Bahrami, Khodayar; Short, Billie Lou; Luban, Naomi L.C.

doi:10.1097/01.pcc.0000102225.49058.4b

Cited by 11 publications

(13 citation statements)

References 37 publications

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“…It is important to note that when the transfusion rate was slower than the rapid manual push (e.g., 2 mL/min), our results showed only minimal increased hemolysis using the one‐way valve. At least one previous study using a syringe pump and small‐bore central venous catheter found no significant hemolysis with flow rates up to 20 mL/hr . However, another report described significant hemolysis using catheters smaller than 22‐gauge and manual syringe push .…”

Section: Discussionmentioning

confidence: 99%

“…At least one previous study using a syringe pump and small-bore central venous catheter found no significant hemolysis with flow rates up to 20 mL/hr. 14 However, another report described significant hemolysis using catheters smaller than 22-gauge and manual syringe push. 8 High and nonuniform pressures during rapid manual transfusion may contribute to increased Hct Change in Hct * The time required for simulated transfusion of 4.5 mL of RBCs was measured using a manual stopwatch for 2 of the 3 units tested by manual simulated transfusion.…”

Section: Discussionmentioning

confidence: 99%

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Mechanical hemolysis in pediatric patients associated with rapid transfusion and one‐way valve

et al. 2018

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Mechanical hemolysis in pediatric patients associated with rapid transfusion and one‐way valve

et al. 2018

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“…In this research, the average time of erythrocyte storage was seven and a half days, ranging from one to 25 days. According to researchers, the period of storage of red blood cells of up to ten days is considered short, and the erythrocytes, consequently, considered young, while the period above 25 days is considered prolonged (13) .…”

Section: Peripherally Inserted Central Catheter Obstruction In Packed...mentioning

confidence: 99%

“…Existing evidence on erythrocyte transfusion in the PICC and its relationship with occurrence of obstruction are rare. When performed, the studies are directed to tests in laboratory to relate the occurrence of hemolysis with the rate of infusion of the blood, catheters and equipment used for infusion (12)(13)(14) .…”

Section: Introductionmentioning

confidence: 99%

Peripherally inserted central catheter obstruction in packed red blood cell transfusions in neonates

et al. 2022

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Objectives: to estimate incidence and free time of peripherally inserted central catheter obstruction in newborns undergoing red blood cell transfusion in the first 24 hours after the procedure. Methods: a longitudinal study, carried out with neonates in Neonatal Intensive Care Unit at a teaching hospital in Paraná, between January and July 2019. The sample consisted of 46 transfusion events performed in neonates through a peripherally inserted central catheter. Analysis performed according to descriptive statistics. Results: thirty-one catheters were analyzed, inserted in 24 neonates, through which 46 red blood cell transfusions were performed. Most neonates were male, gestational age <32 weeks, weight <1,500 grams, hospitalized mainly for prematurity. Among the 31 catheters, one (3.2%) presented obstruction after transfusion. Conclusions: The occurrence of obstructions immediately after transfusion was low and the catheters remained complication free for the next 24 hours.

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“…However, some people prefer to reserve these catheters for nutrient solutions or drugs because of concerns about clogging a small-bore central catheter with a blood transfusion. 1 Hence, small peripheral needles are often used for transfusions.…”

Section: Venous Accessmentioning

confidence: 99%

Technical issues in neonatal transfusions

Sloan

2008

Immunohematology

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Neonatal transfusions provide challenges at several steps in the process. Neonates are often transfused with relatively small volumes at slow flow rates from syringes,whereas at other times they require relatively massive transfusions or exchange transfusions. To facilitate these specialized transfusions, blood banks often modify their procedures to provide small volumes of blood components that are sometimes dispensed in syringes or to reconstitute whole blood for exchange transfusions. Hospitals must implement policies and procedures to ensure that the blood components are transfused safely when using these specialized techniques for infants. Nevertheless, some issues remain in many hospitals, such as the difficulty in safely warming blood components for neonatal transfusions and the difficulties in using approved labels for small containers that are sometimes prepared at the bedside. Immunohematology 2008;24:4–9.

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Feasibility of red blood cell transfusion through small bore central venous catheters used in neonates

Abstract: No clinically significant hemolysis was evidenced with red blood cell transfusion through small-bore central venous catheters when using fresher or older CPDA-1 red blood cells at 2 or 20 mL/hr.

Cited by 11 publications

References 37 publications

Mechanical hemolysis in pediatric patients associated with rapid transfusion and one‐way valve

Mechanical hemolysis in pediatric patients associated with rapid transfusion and one‐way valve

Peripherally inserted central catheter obstruction in packed red blood cell transfusions in neonates

Technical issues in neonatal transfusions

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