Feasibility of strain and strain rate imaging for the assessment of regional left atrial deformation: A study in normal subjects

Sirbu, C; Herbots, Lieven; D'hooge, Jan; Claus, Piet; Marciniak, Anna; Langeland, Tor; Bijnens, Bart; Rademakers, Frank; Sutherland, George R.

doi:10.1016/j.euje.2005.06.001

Cited by 185 publications

(167 citation statements)

References 30 publications

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“…In this manner, STE allows for the assessment of myocardial function independent of cardiac translation and angle of insonation 3, 4, 10. In people, reference range values, feasibility, and reproducibility of STE for the study of LA mechanics have been extensively documented 12, 13, 14, 15. Furthermore, the clinical and prognostic importance of STE variables has been demonstrated in numerous pathophysiologic conditions typically associated with abnormal LA function, including MMVD, atrial fibrillation, systemic hypertension, and dilated, as well as hypertrophic, cardiomyopathy 3, 4, 10, 16, 17.…”

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confidence: 99%

Assessment of Left Atrial Deformation and Function by 2‐Dimensional Speckle Tracking Echocardiography in Healthy Dogs and Dogs With Myxomatous Mitral Valve Disease

Toaldo

Romito

Guglielmini

et al. 2017

Veterinary Internal Medicne

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BackgroundThe assessment of left atrial (LA) function by 2‐dimensional speckle tracking echocardiography (STE) holds important clinical implications in human medicine. Few similar data are available in dogs.ObjectivesTo assess LA function by STE in dogs with and without myxomatous mitral valve disease (MMVD), analyzing LA areas, systolic function, and strain.AnimalsOne hundred and fifty dogs were divided according to the American College of Veterinary Internal Medicine classification of heart failure: 23 dogs in class A, 52 in class B1, 36 in class B2, and 39 in class C + D.MethodsProspective observational study. Conventional morphologic and Doppler variables, LA areas, and STE‐based LA strain analysis were performed in all dogs and results were compared among groups. Correlation analysis was carried out between LA STE variables and other echocardiographic variables.ResultsVariability study showed good reproducibility for all the tested variables (coefficient of variation <16%). Left atrial areas, fractional area change, peak atrial longitudinal strain (PALS), peak atrial contraction strain, and contraction strain index (CSI) differed significantly between groups B2 and C + D and all the other groups (overall P < .001), whereas only PALS differed between groups B1 and A (P = .01). Left atrial areas increased with progression of the disease, whereas LA functional parameters decreased. Only CSI increased nonsignificantly from group A to group B1 and then progressively decreased. Thirty‐one significant correlations (P < .001, r > .3) were found between conventional left heart echocardiographic variables and LA areas and strain variables.Conclusions and Clinical ImportanceLeft atrial STE analysis provides useful information on atrial function in the dog, highlighting a progressive decline in atrial function with worsening of MMVD.

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confidence: 99%

Assessment of Left Atrial Deformation and Function by 2‐Dimensional Speckle Tracking Echocardiography in Healthy Dogs and Dogs With Myxomatous Mitral Valve Disease

Toaldo

Romito

Guglielmini

et al. 2017

Veterinary Internal Medicne

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“…S/SR imaging methods have been used in the assessment of LV function in many cardiovascular diseases (14)(15)(16)(17). S/SR imaging derived from TDI has been validated by quantitative assessment of regional LA deformation in healthy subjects (10,14). In a few studies, LA deformation has been shown to be affected in various etiologies.…”

Section: Introductionmentioning

confidence: 99%

“…Atrial mechanical cycle is consisted of three phases: reservoir phase (RP) during LV systole, conduit phase (CP) during early and mid-period of the ventricular diastole, and pump phase (PP) which enhance LV filling during late diastole (9)(10)(11). Although LA volumes assessed by conventional echocardiography provide information about the global function, it remains inadequate for the quantitative assessment of myocardial function separately during each of these phases.…”

Section: Introductionmentioning

confidence: 99%

Quantitative assessment of the left atrial myocardial deformation in patients with chronic mitral regurgitation by strain and strain rate imaging: an observational study

Aksakal¹,

Şimşek²,

Sevimli³

et al. 2012

Anadolu Kardiyol Derg

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“…2,28 Immediately after the BMV procedure a repeat echocardiogram was performed to define the success of procedure as mentioned previously. 15,[16][17][18][19][20][21][22][23][24][25][26][27][28][29] All patients, in whom BMV was successful, underwent a repeat echocardiographic evaluation 24-48 hours after the procedure for the measurement of post-procedural parameters.…”

Section: Echocardiographymentioning

confidence: 99%

“…20 The left atrial phasic volumes were calculated by the modified Simpson's method from the apical four chamber view at the onset of P-wave on the ECG [pre-atrial contraction volume, V p ( Figure 1 . [21][22][23] These values were corrected for the body surface area (BSA). For the assessment of LA mechanical functions, the following indices calculated from the volumes were used.…”

Section: Echocardiographymentioning

confidence: 99%

Acute Impact of Balloon Mitral Valvotomy on Left Atrial Functions in Mitral Stenosis

Beig¹,

Dar²,

Kumar³

et al. 2017

JCDR

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Background: Rheumatic mitral stenosis (MS) is associated with progressive impairment of left atrial (LA) mechanical functions. This study was conducted to assess the acute impact of Balloon Mitral Valvotomy (BMV) on these functions. Methods: This single centre observational study included 25 patients with severe MS (aged 34.1 ± 7.1 years, with mean mitral valve area of 0.74 ± 0.13 cm²), in sinus rhythm, who underwent successful BMV at our hospital. Phasic LA volumes (V max : maximal LA volume, V min : minimal LA volume, and V p : LA volume at the onset of P-wave) were measured by modified Simpson's method. Parameters of LA reservoir function i.e. LA total emptying fraction (LATEF) and LA expansion index (LAEI); conduit function i.e. LA passive emptying fraction (LAPEF); and pump function i.e. LA active emptying fraction (LAAEF) were calculated from these volumes. All these parameters were evaluated before and 24-48 hours after BMV. Results: Successful BMV led to significant reduction in V max (p < 0.001), V min (p < 0.001), and V p (p < 0.001). There was a significant increase in LATEF (p= 0.001) and LAEI (p= 0.002). LAPEF increased insignificantly (p= 0.057), while there was no significant change in LAAEF (p =0.127) after BMV. Conclusion: Successful BMV leads to early improvement in left atrial reservoir and conduit functions, without significantly affecting left atrial pump function. Whether these acute changes translate into long term left atrial reverse remodelling and clinical benefits thereof needs to be established by further studies.

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Feasibility of strain and strain rate imaging for the assessment of regional left atrial deformation: A study in normal subjects

Abstract: SR/epsilon imaging for the quantification of longitudinal myocardial LA deformation was shown to be feasible and the normal values were reported and validated. These data may improve the understanding of the LA pathophysiology.

Cited by 185 publications

References 30 publications

Assessment of Left Atrial Deformation and Function by 2‐Dimensional Speckle Tracking Echocardiography in Healthy Dogs and Dogs With Myxomatous Mitral Valve Disease

Assessment of Left Atrial Deformation and Function by 2‐Dimensional Speckle Tracking Echocardiography in Healthy Dogs and Dogs With Myxomatous Mitral Valve Disease

Quantitative assessment of the left atrial myocardial deformation in patients with chronic mitral regurgitation by strain and strain rate imaging: an observational study

Acute Impact of Balloon Mitral Valvotomy on Left Atrial Functions in Mitral Stenosis

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