Feasibility of supercritical fluid chromatography-chemiluminescent nitrogen detection with open tubular columns

Optimization of Chemiluminescent Nitrogen Detection for Packed-Column Supercritical Fluid Chromatography with Methanol-Modified CO2

“…Their system required no postcolumn split. Our MDQ, however, is more than the 0.06 ng of N for open tubular SFC-CLND using pure CO 2 …”

“…column is much better than that previously reported for SFC-CLND. Shi et al obtained a MDQ of 0.3 ng of N at the detector (4.2 ng on column) using 5% methanol-modified packed-column SFC-CLND and 0.06 ng of N with open tubular SFC-CLND with pure CO 2 …”

“…GC and HPLC applications using the CLND for biochemical, food, flavor, pesticide residue, environmental, pharmaceutical, and petroleum samples have been reported. − SFC-CLND was first reported by Shi et al, who used open tubular columns without a postcolumn split. They found that the detector response was affected by the restrictor position in the pyrolysis chamber and the pyrolysis oxygen flow rate.…”

Supercritical Fluid Chromatography and Extraction

“…Shi et al coupled a chemiluminescent nitrogen detector with otSFC detecting as little as 60 pg of N ( , ). Shi et al later successfully coupled this detector with pcSFC using methanol-modified CO 2 mobile phase with both pressure and modifier gradients ().…”

XIVth International Symposium on Luminescence Spectrometry – Recent advances of luminescence techniques in research and modern technology (ISLS 2010) Extended Abstracts

“…The only CL method previously developed for dimethoate analysis, is based on reaction between ozone and the nitric oxide produced by the pyrolysis, performed in the effluent of a supercritical-fluid chromatography equipment 1 .…”