Feasibility of Using Fat Degeneration of Lumbar Extensor Muscle as an Alternative Diagnostic Criterion for Sarcopenia in Patients with Osteoporotic Vertebral Fractures

Heo, Ju-Yeong; Park, Jihun; Lim, Sung-An; Shim, Seung-Woo; Choi, Yong‐Soo

doi:10.31616/asj.2019.0044

Cited by 4 publications

(3 citation statements)

References 23 publications

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“…The intramuscular FI portion is a non-functional area that increases with age; however, core exercise can slow the change. 30 Because interest in exercise therapy and sarcopenia is growing recently, 8 31 a standardized method for evaluating paraspinal muscle is needed.…”

Section: Discussionmentioning

confidence: 99%

Effect of Muscularity and Fatty Infiltration of Paraspinal Muscles on Outcome of Lumbar Interbody Fusion

2023

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Background Lumbar paraspinal muscles play an important role in maintaining global spinal alignment and are associated with lower back pain; however, only a few studies on the effect of the paraspinal muscles on the surgical outcome exist. Therefore, this study aimed to analyze the association of preoperative muscularity and fatty infiltration (FI) of paraspinal muscles with the outcome of lumbar interbody fusion. Methods Postoperative clinical and radiographic outcomes were analyzed in 206 patients who underwent surgery for a degenerative lumbar disease. The preoperative diagnosis was spinal stenosis or low-grade spondylolisthesis, and the surgery performed was posterior lumbar interbody fusion or minimally invasive transforaminal lumbar interbody fusion. Indications for surgery were a complaint of severe radiating pain that did not improve with conservative treatment and neurological symptoms accompanied by lower extremity motor weakness. Patients with fractures, infections, tumors, or a history of lumbar surgery were excluded from this study. Clinical outcome measures included functional status, measured using the Oswestry disability index (ODI) and visual analog scale (VAS) score for lower back and leg pain. Other radiographic parameters included measures of spinal alignment, including lumbar lordosis, pelvic tilt, sacral slope, pelvic incidence, C7 sagittal vertical axis, and pelvic incidence-lumbar lordosis mismatch. Lumbar muscularity (LM) and FI were measured preoperatively using a lumbar magnetic resonance image (MRI). Results The high LM group showed more significant improvement in VAS score for lower back pain than the low LM group. In contrast, the VAS score for leg pain demonstrated no statistical significance. The high LM group showed more significant improvement in ODI postoperatively than the medium group. The severe FI group showed more significant improvement in ODI postoperatively, whereas the less severe FI group showed more significant improvement in the sagittal balance postoperatively. Conclusion Patients with high LM and mild FI ratio observed on preoperative MRI demonstrated more favorable clinical and radiographic outcomes after lumbar interbody fusion. Therefore, preoperative paraspinal muscle condition should be considered when planning lumbar interbody fusion.

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Section: Discussionmentioning

confidence: 99%

Effect of Muscularity and Fatty Infiltration of Paraspinal Muscles on Outcome of Lumbar Interbody Fusion

2023

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“…The analysis between sarcopenia delineation criterions and fat deposition in the aforementioned muscle showed an unfavorable correlation with walking velocity, hand grip power. Also, fatty infiltration of the specific muscle demonstrates a strong correlation with osteoporotic vertebral fractures 19 . Similarly, through MRI morphometrical analysis of superficial and deep paravertebral muscles of the cervical spine, it has been demonstrated that deep flexor sarcopenia is a negative prognostic factor in terms of amelioration following anterior cervical diskectomy for single-level cervical disc disease 20 .…”

Section: Mri Characteristics and Capabilities Contributing To High Di...mentioning

confidence: 99%

The assessment of sarcopenia using magnetic resonance imaging

Bisyri¹,

Lambrou²

2022

JRPMS

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frailty, cardiac and pulmonary disease, mental decline, increased risk for falls, fractures and hospitalization. Even though recognizing sarcopenia can be done through a special questionnaire filling in and clinical test performance, imaging plays a determinant role in sarcopenia's diagnosis confirmation by estimating the muscle quality and quantity. There are various imaging methods that can be used for this purpose, such us ultrasonography, dual energy-ray absorptiometry, computed tomography and Magnetic Resonance Imaging (MRI) 5 .The aim of this review is to present the applications of MRI in sarcopenia assessment, by giving prominence to the advantages of this imaging modality, the specific MRIderived surrogate parameters/biomarkers of sarcopenia and the MRI techniques serving that scope.

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“…Another limitation concerned the measure of fat infiltration. Fat infiltration derived from T2-weighted images [23,56,69,123,124], risks overestimating fatty muscle degeneration because water and other tissues in addition to fat appear hyperintense. The Dixon MRI technique has demonstrated its superiority over and T2weighted imaging techniques in terms of fat fraction quantification [125].…”

Section: Limitationsmentioning

confidence: 99%

Age-related degeneration of lumbar muscle morphology in healthy younger versus older men

et al. 2020

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Aim:The aim of this study was to evaluate age-related changes in lumbar paravertebral muscle (LPM) morphology in healthy younger and older adult men. Methods: T2-weighted axial MRI of the lumbar spine were obtained for 12 healthy older (67.3 ± 6.0 years) and younger (24.7 ± 3.1 years) men. Normalised muscle volume (NMV) and muscle fat infiltrate (MFI) were determined bilaterally for the psoas (PS), quadratus lumborum (QL), erector spinae (ES) and multifidus (MF). MANOVA was used to compare NMV and MFI between age groups. Follow-up ANOVA compared NMV and MFI for each muscle between age groups, with physical activity (PA) as a covariate. Stepwise regression was used to explore the association between muscle morphology. Results: NMV of the ES and QL were significantly lower in the older group (OG) (p ¼ 0.040 and p < 0.001, respectively). MFI across all muscles was significantly greater in the OG (p < 0.001). PA did not moderate the relationship between aging and muscle degeneration. Non-dominant handgrip strength was associated with NMV (p ¼ 0.003). Conclusions: Age-related atrophy is muscle specific in the lumbar spine; changes in lumbar musculature is independent of PA, handgrip strength may reflect morphological changes in the postural muscles with age. This study supports establishing effective targeted exercise interventions in the lumbar musculature.

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Feasibility of Using Fat Degeneration of Lumbar Extensor Muscle as an Alternative Diagnostic Criterion for Sarcopenia in Patients with Osteoporotic Vertebral Fractures

Cited by 4 publications

References 23 publications

Effect of Muscularity and Fatty Infiltration of Paraspinal Muscles on Outcome of Lumbar Interbody Fusion

Effect of Muscularity and Fatty Infiltration of Paraspinal Muscles on Outcome of Lumbar Interbody Fusion

The assessment of sarcopenia using magnetic resonance imaging

Age-related degeneration of lumbar muscle morphology in healthy younger versus older men

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