This work evaluated the effect of Anti-Stripping Agents (ASAs) on performance behavior of bitumen and high and intermediate temperature performance of SMA mixtures modified by Poly Phosphoric Acid (PPA), Warm Mix Asphalt (WMA) and Styrene-Butadiene Rubber (SBR) additive. Through this paper, the AC-60/70 and AC-85/100 penetration grade bitumens were used as base bitumen. Moreover, three liquid ASAs (ASA (1), ASA (2), ASA (3)), PPA (1% by weight of bitumen), SBR (2% by weight of binder), and two types of warm mix additives (3% Sasobit and 0.3% Zycotherm) were used as a mixture modifier. For evaluating the performance behavior of bitumen, the rotational viscosity, Dynamic Shear Rheometer, and Bending Beam Rheometer, Multiple Stress Creep Recovery (MSCR), and linear Amplitude Sweep (LAS) tests were implemented. Moreover, Resilient Modulus (Mr), Indirect Tensile Strength (ITS), dynamic creep, wheel track, and Four-Point Beam Fatigue (FPB) tests were performed to investigate the performance of mixture samples. Based on the outcomes of the MSCR test, the utilization of SBR/PPA additive and ASAs decreased the Jnr value. Among modified binders, the binders modified by ASA (2) have the lowest Jnr value followed by binders modified by ASA (1) and ASA (3). According to the outcomes of LAS test, the utilization of ASAs leads to increase in the fatigue life of the original binder. According to the outcomes, the utilization of WMA additives and ASAs caused the Mr, ITS, rutting resistance, and fatigue life to increase. Among ASAs, the ASA (2) has the greatest influence on enhancing the performance of mixtures. Based on results, Sasobit additive has a better effect than Zycotherm on enhancing the properties of samples.