Feathers as bioresource: Microbial conversion into bioactive protein hydrolysates

Callegaro, Kelly; Welter, Nicoly; Daroit, Daniel Joner

doi:10.1016/j.procbio.2018.09.002

Cited by 57 publications

(28 citation statements)

References 46 publications

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“…The foreseeable implication of the bioconversion of keratinous biomass into utilizable units include food chain nourishment, bio-geo-ecological balance, and safety to public and animal health as pathogens would have lost habitation consequent to organic matter decomposition (Kowalczyk et al, 2018;De Oliveira Martinez et al, 2020). Another significant contribution of the keratinase producing microbes is the recycling of refractory materials with keratin composition, thus, reducing the pollution levels of the planet (Callegaro et al, 2018).…”

Section: Environmental Impact Of Keratinous Waste and The Ecological mentioning

confidence: 99%

Microbial Keratinase: Next Generation Green Catalyst and Prospective Applications

et al. 2020

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The search for novel renewable products over synthetics hallmarked this decade and those of the recent past. Most economies that are prospecting on biodiversity for improved bio-economy favor renewable resources over synthetics for the potential opportunity they hold. However, this field is still nascent as the bulk of the available resources are non-renewable based. Microbial metabolites, emphasis on secondary metabolites, are viable alternatives; nonetheless, vast microbial resources remain under-exploited; thus, the need for a continuum in the search for new products or bio-modifying existing products for novel functions through an efficient approach. Environmental distress syndrome has been identified as a factor that influences the emergence of genetic diversity in prokaryotes. Still, the process of how the change comes about is poorly understood. The emergence of new traits may present a high prospect for the industrially viable organism. Microbial enzymes have prominence in the bio-economic space, and proteases account for about sixty percent of all enzyme market. Microbial keratinases are versatile proteases which are continuously gaining momentum in biotechnology owing to their effective bio-conversion of recalcitrant keratin-rich wastes and sustainable implementation of cleaner production. Keratinase-assisted biodegradation of keratinous materials has revitalized the prospects for the utilization of cost-effective agro-industrial wastes, as readily available substrates, for the production of high-value products including amino acids and bioactive peptides. This review presented an overview of keratin structural complexity, the potential mechanism of keratin biodegradation, and the environmental impact of keratinous wastes. Equally, it discussed microbial keratinase; vis-à-vis sources, production, and functional properties with considerable emphasis on the ecological implication of microbial producers and catalytic tendency improvement strategies. Keratinase applications and prospective high-end use, including animal hide processing, detergent formulation, cosmetics, livestock feed, and organic fertilizer production, were also articulated.

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Section: Environmental Impact Of Keratinous Waste and The Ecological mentioning

confidence: 99%

Microbial Keratinase: Next Generation Green Catalyst and Prospective Applications

et al. 2020

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“…We produced high levels of the keratinase, KerK (approximately 1000 U mL −1 ) as did another group 5 ; however, this approach was ultimately disappointing, since without a sulfitolysis agent, keratinase feather hydrolyzation has very low efficiency and the cost of recombinant keratinase preparation is considerable. Microbial fermentation is the most economical method and there have been many attempts to isolate natural FDB; however, most FDB is insufficiently efficient for application in industry-scale feather hydrolysis 1,39,40 . Keratinase overexpressing bacteria have been generated that can hydrolyze feather using their own reducing power, with limited success.…”

Section: Discussionmentioning

confidence: 99%

“…The poultry industry generates increasing amounts of feather waste; according to the Alltech Global Feed Survey, broiler feed production in 2018 was 0.3 billion tons, which estimated to produce about 0.2 billion tons of chicken and more than 10 million tons of chicken feathers. Numerous disulfide bonds make the feather matrix highly durable and resistant to chemical and physical factors 1 .…”

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The feather degradation mechanisms of a new Streptomyces sp. isolate SCUT-3

Liang

Yao

et al. 2020

Commun Biol

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Feather waste is the highest protein-containing resource in nature and is poorly reused. Bioconversion is widely accepted as a low-cost and environmentally benign process, but limited by the availability of safe and highly efficient feather degrading bacteria (FDB) for its industrial-scale fermentation. Excessive focuses on keratinase and limited knowledge of other factors have hindered complete understanding of the mechanisms employed by FDB to utilize feathers and feather cycling in the biosphere. Streptomyces sp. SCUT-3 can efficiently degrade feather to products with high amino acid content, useful as a nutrition source for animals, plants and microorganisms. Using multiple omics and other techniques, we reveal how SCUT-3 turns on its feather utilization machinery, including its colonization, reducing agent and protease secretion, peptide/amino acid importation and metabolism, oxygen consumption and iron uptake, spore formation and resuscitation, and so on. This study would shed light on the feather utilization mechanisms of FDBs.

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“…Tais potenciais também foram reportados in vitro para hidrolisados de penas produzidos por três linhagens queratinolíticas de Bacillus sp. (Callegaro et al, 2018). Em testes in vivo, a adição de hidrolisados de penas à dieta de ratos Wistar resultou na redução de indicadores relacionados ao estresse oxidativo em diversos órgãos destes animais (Fahkfahk et al, 2012).…”

Section: Atividades Biológicasunclassified

“…Em testes in vivo, a adição de hidrolisados de penas à dieta de ratos Wistar resultou na redução de indicadores relacionados ao estresse oxidativo em diversos órgãos destes animais (Fahkfahk et al, 2012). Desta forma, a conversão microbiana pode representar uma importante tecnologia para a obtenção de hidrolisados e peptídeos bioativos com potencial relevância para a saúde humana a partir de penas de frango, materiais abundantes e de baixo custo (Lemes et al, 2016;Callegaro et al, 2018).…”

Section: Atividades Biológicasunclassified

SUB-BOSQUE EM UM TESTE DE PROGÊNIES E PROCEDÊNCIAS DE Eucalyptus urophylla S.T. BLAKE

Cambuim¹,

Pupin²,

Zaruma³

et al. 2020

Sistematização De Uma Agenda Para Questões Socioambientais

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Todo o conteúdo deste livro está licenciado sob uma Licença de Atribuição Creative Commons. Atribuição 4.0 Internacional (CC BY 4.0). O conteúdo dos artigos e seus dados em sua forma, correção e confiabilidade são de responsabilidade exclusiva dos autores. Permitido o download da obra e o compartilhamento desde que sejam atribuídos créditos aos autores, mas sem a possibilidade de alterá-la de nenhuma forma ou utilizá-la para fins comerciais.

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Feathers as bioresource: Microbial conversion into bioactive protein hydrolysates

Cited by 57 publications

References 46 publications

Microbial Keratinase: Next Generation Green Catalyst and Prospective Applications

Microbial Keratinase: Next Generation Green Catalyst and Prospective Applications

The feather degradation mechanisms of a new Streptomyces sp. isolate SCUT-3

SUB-BOSQUE EM UM TESTE DE PROGÊNIES E PROCEDÊNCIAS DE Eucalyptus urophylla S.T. BLAKE

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