Due to the stochastic nature of environmental loadings, a lot of interest is paid in the discovery of possible damages of the involved equipment in modern industry. In wind turbines’ blades, the development of a smart structural health monitoring system is essential. In this paper, a large-scale composite wind turbine blade model is designed and used for the detection of several damage scenarios. The process is mainly based on the development of monitoring techniques which exploit the capabilities of artificial neural networks. These techniques can provide the exact position of possible damages, under given external loading scenarios. Moreover, the use of such methods decreases significantly the need of external intervention and at the same time it increases the accuracy of the whole approach. The above processes are simulated using the finite element method. The goal is to develop a neural network which realizes the correlation of measurements with damage patterns. The goal is focused on the solution of inverse problems involving elastically deformable structures, based on remote mechanical measurements. The correlation between measurements and damages, which is much more complicated in comparison to image analysis, is studied by means of neural networks.