Features and Outcome of Surgical Management of Spinal Tumors in a Cohort of Nigerian Patients

Adeolu, Augustine Abiodun; Oyemolade, Toyin Ayofe; Salami, Ayodeji; Adigun, Tinuola; Malomo, A O; Akang, E. E. U.; Shokunbi, Temitayo

doi:10.1016/j.wneu.2015.05.081

Cited by 7 publications

(12 citation statements)

References 9 publications

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“…The three studies eligible for analysis identified internal validity integrity and homogeneity in sample datasets in accordance to the number of patients in each spinal neoplasm prevalence group (11,(14)(15) . Oxford CEBM level of evidence-based medicine criteria analyses (13) classified clinical appraisal quality as level 4 in the cross-sectional study (11) and level 3 in the two case-series studies (14)(15) . Randomized controlled trials were absent in this literature search.…”

Section: Systematic Literature Review Resultsmentioning

confidence: 99%

“…This secondary outcome indicated that spinal intradural neoplasms were prevalent when compared with spinal metastases, the latter the most common histologic tumor type group. Comparisons in spinal neoplasms census concerning the systematic literature review indicated that 191 (22.05%) patients were operated for spinal metastases, 83 (9.59%) for epidural primary neoplasms and 592 (68.36%) for intradural neoplasms, in regard to the 3 reports cohorts of 866 (100%) patients operated for spinal and spinal tissue neoplasms (11,(14)(15) .…”

Section: Systematic Literature Review Resultsmentioning

confidence: 99%

“…Adeolu et al, 2015 (14) reports the histologic pattern, anatomic distribution and, surgical outcomes in patients with spinal tumors. Study is conducted in a single hospital performed by a neurosurgical division located in Nigeria, sub-Saharan Africa.…”

Section: Systematic Literature Review Resultsmentioning

confidence: 99%

“…This cross-sectional survey and literature review indicate that spinal intradural neoplasms are prevalent when compared to spinal metastases in performed neurosurgical procedures. Survey also indicates that spinal metastases are the most common histologic tumor type group (11,(14)(15) . The aforementioned information is the encountered epidemiological gap in literature and the proposed reason for this research.…”

Section: Discussionmentioning

confidence: 99%

“…This unchanging trend is in accordance to this studies descriptive census finding of an unchanging trend for operated spinal metastases in the 21-year times series and perhaps indicates equipoise between non-surgical and surgical treatment for patients harboring advanced cancer in this specific Institution. In regard to the other two analyzed reports included in the systematic review (14)(15) trend analysis cannot be performed due to absent data in regard to overall performed neurosurgeries. These threeneurosurgical divisions operating profiles analyzed in the systematic review indicate that intradural spinal neoplasms prevail in regard to surgically treated spinal metastases (11,(14)(15) .…”

Section: Discussionmentioning

confidence: 99%

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Prevalence of spinal metastases: a descriptive cross-sectional update and literature review / Prevalência em metástases espinais: atualização de estudo transversal descritiva e revisão da literatura

Daniel

Veiga

2019

Arq Med Hosp Fac Cienc Med Santa Casa São Paulo

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Introduction: A measure of an epidemiological event occurrence contributes in institutional health planning, resource allocation, sickness trend prediction and a surgical divisions operating profile. Objective: Census in prevalence of spinal epidural metastases among spinal and spinal tissue neoplasms in the neurosurgical context is the encountered epidemiological literature gap and the proposed reason for this research. Methods: A surgically treated spinal neoplasms patient descriptive cross-sectional update census was performed between February 1997 and January 2018 in a single neurosurgical division. In addition, using the systematic research method for literature review, authors selected comparative descriptive studies in patients submitted to surgical procedures for spinal epidural metastases, epidural primary and intradural neoplasms. The methodological quality analysis was in accordance to the Oxford Centre for Evidence-Based Medicine. Results: The primary outcome obtained in the cross-sectional descriptive update study indicated that 128 neurologically symptomatic patients were submitted to surgical procedures for spinal metastases and represented 0.84% of the 15,061-neurosurgical procedures. As for the secondary outcome, literature review identified 3 comparative studies: 1 cross-sectional and 2 case-series. In a cohort of 866 (100%) patients submitted to surgical treatment, 191 (22.05%) patients were operated for spinal metastases, 83 (9.59%) for epidural primary neoplasms and 592 (68.36%) for intradural neoplasms. Clinical appraisals identified Grade C recommendation for the 3 included items. Conclusion: Spinal intradural neoplasms are prevalent when compared to spinal metastases and spinal metastases are the most common histologic tumor type group in patients submitted to surgical treatment.Keywords: Neoplasm metastasis; Epidemiology; Spine; Surgical procedures, operativeRESUMOIntrodução: À medida que ocorra um evento epidemiológico, o mesmo contribuirá no planejamento do atendimento à saúde numa Instituição no tocante à alocação de recursos, à previsão de tendências de doenças e a caracterização do perfil de procedimentos cirúrgicos de um departamento de cirurgia. Objetivo: Estabelecer censo na prevalência de metástases epidurais dentre as neoplasias da coluna vertebral e do tecido nervoso nela contido. No contexto neurocirúrgico é a lacuna epidemiológica encontrada na literatura e o motivo proposto desta pesquisa. Métodos: Foi realizado um censo de atualização descritiva transversal de pacientes submetidos a cirurgias espinhais no período entre fevereiro de 1997 e janeiro de 2018 em uma única divisão neurocirúrgica. Ademais, utilizando o método de pesquisa sistemática para revisão da literatura, os autores selecionaram estudos descritivos comparativos de pacientes com diagnóstico de neoplasias epidurais secundárias, epidurais primárias e intradurais submetidos a procedimentos cirúrgicos em coluna vertebral. A análise metodológica da qualidade dos estudos foi realizada de acordo com o Oxford Center for Evidence-Based Medicine. Resultados: O desfecho primário obtido no estudo de atualização descritiva transversal indicou que 128 pacientes neurologicamente sintomáticos foram submetidos a procedimentos cirúrgicos em metástases espinhais e representaram 0,84% do total de 15.061 procedimentos neurocirúrgicos em geral. Quanto ao desfecho secundário, a revisão de literatura identificou 3 estudos comparativos: 1 transversal e 2 séries de casos. Em uma coorte de 866 (100%) pacientes submetidos a tratamento cirúrgico, 191 (22,05%) foram operados para metástases espinhais, 83 (9,59%) para neoplasias primárias epidurais e 592 (68,36%) para neoplasias intradurais. A análise metodológica da qualidade dos estudos identificou recomendação Grau C para os 3 itens incluídos. Conclusão: As neoplasias intradurais da coluna vertebral são prevalentes quando comparadas às metástases espinhais e estas últimas são o tipo histológico mais comum em pacientes submetidos a tratamento cirúrgico em coluna vertebral.Descritores: metástase neoplásicas, Epidemiologia, Coluna vertebral, Procedimentos cirúrgicos operatórios

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