2017
DOI: 10.1134/s1990750817010085
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Features of blood-brain barrier formation affected by the modulation of HIF activity in astroglial and neuronal cells in vitro

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“…We have shown before that maturity of BMECs is partially under the control of HIF-1 expression in perivascular astrocytes [ 84 ]. The molecular mechanism of barriergenesis, which has been reviewed elsewhere [ 85 ], includes the activity of numerous growth factors, neuromediators, and cytokines released from the cells of the neurovascular unit: VEGF, PDGF, Ang-1, cyclophilin, MMP, etc.…”
Section: Functional Competence Of Cerebral Endothelial Cells and Thei...mentioning
confidence: 99%
“…We have shown before that maturity of BMECs is partially under the control of HIF-1 expression in perivascular astrocytes [ 84 ]. The molecular mechanism of barriergenesis, which has been reviewed elsewhere [ 85 ], includes the activity of numerous growth factors, neuromediators, and cytokines released from the cells of the neurovascular unit: VEGF, PDGF, Ang-1, cyclophilin, MMP, etc.…”
Section: Functional Competence Of Cerebral Endothelial Cells and Thei...mentioning
confidence: 99%