Features of Clinical Manifestations of Disease and Psychological Status of Adolescents With Bronchial Asthma of Various Levels of Control and the Influence of Risk Factors

Protsiuk, T. L.; Yablon, Olga; Protsiuk, L. O.; Bykovska, Olga A.; Herasymova, O. V.; Kapitan, Tetiana V.

doi:10.36740/wlek201905114

Cited by 3 publications

(1 citation statement)

References 15 publications

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“…Having analyzed obtained data, we come across that we get similar results as those, which were published in scientific literature -in pediatric patients with chronic viral hepatitis B and C, as with others chronic diseases, anxiety degree rises with progression of the disease; de Ritis ratio was detected as independent predictor of liver fibrosis progression [8,10,11].…”

Section: педіатрія / Pediatricssupporting

confidence: 75%

Patterns of Liver Injury and Anxiety Degree in Pediatric Patients With Chronic Viral Hepatitis B and C as Predictors of Liver Fibrosis Prognosis

Nezgoda,

Demchyshyn

2023

VPBM

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Connection of the publication with planned research works.The scientific work is a fragment of the scientific topic: «The course of viral and bacterial infections in children, depending on genetic, immunological, metabolic and morphological factors» (state registration number -0120U100609). Introduction.Chronic viral hepatitis B (CVHB) and C (CVHC) are an important medical and social problem of hepatology at the current stage. According to official data, there are about 2 million people in Ukraine suffering from chronic viral hepatitis. This problem is also relevant among children [1]. CVHB in children who were infected at birth has an asymptomatic course and is characterized by a long immunotolerant phase and does not require routine treatment [2]. However, in patients who were infected during the first years of life, the progression of CVHC is faster [3].According to WHO reports, about 2.2-3.0% of the world's population (130-170 million people) suffer from CVHC [4]. CVHC in children is mostly asymptomatic, in 4-6% it has a progressive course with the development of fibrosis and cirrhosis of the liver [5].Scientists conduct researches of assessing the rate of formation of liver fibrosis induced by HBV-and HCVviruses and features of forecasting its development, however, mainly in the adult population [6,7].Along with that, in patients with increasing age and progression of liver fibrosis, the manifestations of clinical symptoms of asthenic, astheno-vegetative, hemorrhagic and dyspeptic syndromes, lymphadenopathy and splenomegaly syndrome, extrahepatic manifestations, as well as psycho-emotional, somatopsychic and somatoform disorders are increasing.At the same time, the prevalence of HCV infection in respondents with mental and psychiatric disorders varies from 8% to 31%, which is significantly higher than

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Section: педіатрія / Pediatricssupporting

confidence: 75%

Patterns of Liver Injury and Anxiety Degree in Pediatric Patients With Chronic Viral Hepatitis B and C as Predictors of Liver Fibrosis Prognosis

Nezgoda,

Demchyshyn

2023

VPBM

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Anxiety in asthma: a systematic review and meta-analysis

Baldwin

2021

Psychol. Med.

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BackgroundBackground: Growing evidence from observational studies indicates a high prevalence of anxiety in asthma. However, prevalence rates of coexisting anxiety symptoms and comorbid anxiety disorders vary widely across studies. We aimed to evaluate the associations between anxiety and asthma and provide more precise comorbidity estimates.MethodsWe systematically reviewed the literature from case-controlled studies and conducted a meta-analysis to evaluate the pooled prevalence estimates and risks of anxiety symptoms and anxiety disorders in asthma individuals. Screening, data extraction, and quality assessment were undertaken following PRISMA guidelines for preferred reporting of systematic reviews and meta-analysis. A random-effects model was used to calculate pooled prevalence rates. Meta-analysis was conducted using Review Manager 5.3. Multiple databases including PubMed, ScienceDirect, PsychINFO, and PsycARTICLES were searched for publications before 1 December 2019. The review protocol was registered on PROSPERO (ref: CRD42020176028).ResultsIn total, 19 studies involving 106813 participants were included. The pooled prevalence of anxiety symptoms and anxiety disorders in individuals with asthma was 0.32 (95% CI 0.22–0.43) and 0.24 (95% CI 0.13–0.41), respectively. The risks of coexisting anxiety symptoms and comorbid anxiety disorders were significantly higher in asthma patients than in non-asthma controls indicated by OR 1.89 (95% CI 1.42–2.52; Z = 4.37; p < 0.001) and OR 2.08 (95% CI 1.70–2.56; Z = 6.97; p < 0.001), respectively. Anxiety symptoms and anxiety disorders occur at increased frequency among patients with asthma.ConclusionsOur findings highlight the need for appropriate assessments for these comorbid conditions, which may help to identify a subgroup of patients who might benefit from interventions designed to reduce anxiety and enhance the quality of life.

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Comorbid associations and risk factors for uncontrolled bronchial asthma in adolescents

Evert,

Potupchik,

Muravyova

et al. 2024

Vrach

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Improving the effectiveness of bronchial asthma (BA) treatment in adolescents through early diagnosis and correction of associated pathological conditions, including psychoemotional spectrum disorders, is a pressing issue in modern medicine. Objective. To study disorders of the psychoemotional status in adolescents with uncontrolled BA. Material and methods. Psychoemotional disorders associated with BA have been described, assesses their significance as risk factors for uncontrolled and partially controlled asthma in 212 adolescents aged 12–18 years – patients of the pulmonary allergology center. Using the R. Goodman questionnaire (Strengths and Difficulties Questionnaire, SDQ) we investigated the presence and severity of emotional disorders, determined the values of the total score of the scales and the correlation relationships of the analyzed indicators. Results. The results of our own study revealed higher values of the total score of the scale of the questionnaire "Emotional symptoms" in adolescents with uncontrolled asthma, both boys and girls; the absence of deviations from the norm of the studied characteristics in the overwhelming majority of those examined, regardless of the controllability of asthma, gender and age of adolescents and a more significant contribution of borderline and deviating from the norm indicators in the partially controlled and uncontrolled course of asthma. Conclusion. The authors conclude that the approach to the treatment of uncontrolled asthma should be comprehensive, including mandatory diagnostics and correction of asthma-associated diseases and existing socio-psychological problems in adolescents.

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Features of Clinical Manifestations of Disease and Psychological Status of Adolescents With Bronchial Asthma of Various Levels of Control and the Influence of Risk Factors

Cited by 3 publications

References 15 publications

Patterns of Liver Injury and Anxiety Degree in Pediatric Patients With Chronic Viral Hepatitis B and C as Predictors of Liver Fibrosis Prognosis

Patterns of Liver Injury and Anxiety Degree in Pediatric Patients With Chronic Viral Hepatitis B and C as Predictors of Liver Fibrosis Prognosis

Anxiety in asthma: a systematic review and meta-analysis

Comorbid associations and risk factors for uncontrolled bronchial asthma in adolescents

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