Features of Herd Immunity Against Hepatitis B (HBV) in the Territory of Republic of Sakha (Yakutia), Russian Federation

Abstract

There is new data on the prevalence and characteristics of population immunity against HBV among the indigenous population of the Republic of Sakha (Yakutia) of the Russian Federation. HBV infection in the risk group is significantly higher than in the normal population, in patients with type 2 diabetes, there is a high parenteral infection of HBV, HCV and HBV + HCV (71,5%, 10,8% and 7,5% respectively). It was shown that every other 3-8 years among children and adults of Yakut population living in the Republic of Sakha (Yakutia) (hyperendemic region on HBV), vaccinated at birth against HBV, the frequency of detection of anti-HBs in protective concentrations (> 10 IU / l and higher) is-72.2%. Saving anti-HBs in vaccinated for 8 years indicates a high efficacy of vaccines against hepatitis B.