This paper assesses the relevance of the problem of waste generation and use at sawmills. An analysis of the process of formation of wood waste in the form of sawdust was carried out depending on the equipment and technology used at the enterprise. The feasibility of adding sawdust to wood concrete blocks, which are widely used in the construction of both residential and non-residential buildings and structures, is substantiated. As a result, the purpose of this research was to scientifically substantiate the effectiveness of the production of wood concrete blocks with the addition of sawdust waste in the form of sawdust. During the work, methods of statistical and analytical analysis were used. The results of laboratory studies of the production of wood concrete blocks with the addition of sawdust from softwood and hardwood are presented. The results of laboratory studies were processed, regression dependencies were developed and graphical dependencies were constructed. The results of this research can be widely used in the timber industry, as well as in the production of building materials.