Features of sarcopenia and body composition on the basis of bioimpedance measurements in patients with type 2 diabetes mellitus

Gurieva, I.; Onuchina, Yu. S.; Dymochka, M.A.; Shchelykalina, Svetlana P.; Begma, Inna

doi:10.20953/2224-5448-2017-3-11-19

Cited by 4 publications

(1 citation statement)

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“…В связи с этим современным инструментом ранней диагностики белковой недостаточности является определение саркопении. Саркопения -состояние, характеризующееся снижением мышечной массы и мышечной силы [12,13], является актуальной проблемой для бариатрической хирургии. Таким образом, нарушения белкового обмена после шунтирующих операций являются предметом особого интереса.…”

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Evaluation of the metabolic status and sarcopenia in the long-term period after Roux-en-Y gastric bypass and mini-gastric bypass surgery

Khitaryan

Хациев²,

Mezhunts

et al. 2021

VESTNIK KHIRURGII IMENI I.I.GREKOVA

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INTRODUCTION. Bariatric operations lead to changes in body composition. The desired fat loss may be accompanied by decrease of muscle mass, thus raising the risk of sarcopenia.The OBJECTIVE was to evaluate the long-term results of surgical treatment of morbid obesity and concomitant comorbid conditions, as well as a decrease of muscle mass in the pre - and long-term postoperative period.METHODS AND MATERIALS. This prospective randomized controlled blind trial included the results of treatment of 241 patients. Patients were divided into 2 groups depending on the type of surgical treatment. The first group consisted of 116 people who underwent RYGB; the second group included 125 patients who underwent OAGB/MGB. 83 patients from the first group and 95 patients from the control group at the preoperative stage and 24 months after the operation randomly underwent bioelectrical impedance with the determination of skeletal muscle mass (SMM) and skeletal muscle mass index (SMMI)=SMM/Height2. The calculated SMMI index for men normally corresponds to >10.76 kg/m2; moderate sarcopenia SMMI=8.51–10.75 kg/m2; the SMMI index of ≤8.5 kg/m2 corresponds to severe sarcopenia. For women, this index is normally ≥6.76 kg/m2; moderate – 5.76–6.75 kg/m2; severe sarcopenia ≤5.75 kg/m2. Bioelectrical impedance were performed on a «AVS-01 Medass» bioelectrical impedance body composition analyzer (Russia). RESULTS. The difference in changes in the results of anthropometric indicators, as well as laboratory indicators of diabetes compensation within 24 months in both groups was statistically insignificant (p>0.05). According to bioelectrical impedance data, the incidence of sarcopenia in patient groups was as follows: the initially normal ratio of muscle mass to the square of growth in meters, i.e. normal SMMI in 71 (85.5 %) patients in the group with RYGB, and in 78 (85.7 %) patients in the group with OAGB/MGB. Moderate sarcopenia was detected in 12 (14.5 %) patients with RYGB and 13 (14.3 %) patients with OAGB/MGB. 24 months after the operation, SMMI was distributed as follows – Norm in 59 (71.1 %) patients of the study group and 47 (51.6 %) patients in the control group. Moderate sarcopenia was found in 16 (19.3 %) patients in the group of patients with RYGB, and in 29 (31.9 %) cases in the group of patients with OAGB/MGB. Severe sarcopenia was observed in 8 (9.6 %) patients of the first group and 15 (16.5 %) patients of the second group (p=0.0001).CONCLUSIONS. Bariatric bypass surgery results in significant changes in body composition 24 months after surgery. Bioelectrical impedance allows to effectively detect these changes. The desired weight loss is associated with a significant decrease in skeletal muscle mass, mineral mass. Thus, patients after bypass surgery are at risk of sarcopenia. Sarcopenia is more pronounced in patients after OAGB/MGB than after RYGB.

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Evaluation of the metabolic status and sarcopenia in the long-term period after Roux-en-Y gastric bypass and mini-gastric bypass surgery

Khitaryan

Хациев²,

Mezhunts

et al. 2021

VESTNIK KHIRURGII IMENI I.I.GREKOVA

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Cardiometabolic risk factors in patients with type 2 diabetes and sarcopenia

Samoilova,

Matveeva,

Khoroshunova

et al. 2023

Cardiovasc Ther Prev

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Aim. To analyze risk factors for sarcopenia in atherosclerosis involvement of target organs in patients with type 2 diabetes (T2D).Material and methods. The study included 84 patients with T2D, divided into groups according to the 2019 criteria of the European Working Group on Sarcopenia in Older People (EWGSOP2). All patients were surveyed using a 36-item short-form health survey (SF-36), Sarcopenia and Quality of Life (SarQoL), Strength, Assistance with walking, Rise from a chair, Climb stairs and Falls (SARC-F), grip test, 4-meter walk test, bioelectrical impedance analysis, 24-hour blood pressure monitoring and cardiac ultrasound. Differences were considered significant at p<0,05.Results. Patients with sarcopenia have lower levels of fat, muscle, cell mass, appendicular mass index, fluid, protein, and minerals. In the group with sarcopenia, higher levels of total cholesterol, low-density lipoprotein cholesterol, glycated hemoglobin, and hypocalcemia were detected. Triglyceride levels were high in those with presarcopenia. In the same group, unstable blood pressure, increased myocardial mass and severe lower limb atherosclerosis were recorded.Conclusion. Sarcopenia is one of the important medical and social problems and is accompanied by unfavorable outcomes. The combination of sarcopenia and T2D can contribute to the rapid development of macro- and microangiopathy and increase the cardiovascular risk.

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Modulation of oxidative stress as an early symptom of sarcopenia in type 2 diabetes mellitus

Samoilova,

Khoroshunova,

Matveeva

et al. 2024

Rus. J. Prev. Med.

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Features of sarcopenia and body composition on the basis of bioimpedance measurements in patients with type 2 diabetes mellitus

Cited by 4 publications

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Evaluation of the metabolic status and sarcopenia in the long-term period after Roux-en-Y gastric bypass and mini-gastric bypass surgery

Evaluation of the metabolic status and sarcopenia in the long-term period after Roux-en-Y gastric bypass and mini-gastric bypass surgery

Cardiometabolic risk factors in patients with type 2 diabetes and sarcopenia

Modulation of oxidative stress as an early symptom of sarcopenia in type 2 diabetes mellitus

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