Features of the course of bronchial asthma in children with a history of bronchopulmonary dysplasia

Овсянников, Д Ю; Agarkov, N. M.; Модестов, А. А.; Чичерин, Л П; Kravchuk, D.A.

doi:10.21508/1027-4065-2020-65-4-101-107

Cited by 1 publication

(1 citation statement)

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“…Recently, the role of undifferentiated connective tissue dysplasia (NSTD) has been increasing in the structure of diseases of pediatric patients [1,2]. The study of visceral manifestations of connective tissue dysplasia in children is increasingly reflected in the literature of recent years [1,[3][4][5][6]. Currently, there are indications of the chronological sequence of the formation of various somatic pathologies in children and adolescents in the age aspect [5].…”

Section: Introductionmentioning

confidence: 99%

Dynamics of Phenotypic Manifestations of Connective Tissue Dysplasia in Children with Uroandrological Pathology in the Age Aspect

Mikhailovich¹,

Germanovna²,

Grigorievich³

2021

IJCU

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Introduction. A comparative study of the phenotypic manifestations of undifferentiated connective tissue dysplasia in children of various age groups with urological and andrological pathology is carried out in the article. Materials and methods. The study included 214 children aged 1 month to 17 years with clinical manifestations of undifferentiated connective tissue dysplasia, who were treated in the pediatric uroandrological department for congenital malformations and diseases of the genitourinary system. When establishing undifferentiated connective tissue dysplasia, a generally accepted table of external phenotypic markers was used with their scores. Results. In infants, abnormalities of the auricles and skin are most often detected. In pre-school age, craniocephalic abnormalities, pathology of the osteoarticular system, and abnormalities of the auricles were detected in the largest percentage of cases. The study found that an increase in the percentage of detection of ocular abnormalities increases with age. Moreover, 2 or more eye abnormalities were most common in older children. Anomalies of the oral cavity were diagnosed in only a quarter of infants and were manifested in them by a single sign. In older age categories, anomalies of the oral cavity were observed in more than half of patients, and often they were not single. During the examination of senior schoolchildren, it was noted that all children of this age category had some kind of abnormality from the osteoarticular system, and almost always they were multiple. Conclusion. Somatic manifestations of undifferentiated connective tissue dysplasia are often multi-organ in nature and often have nonspecific clinical symptoms. Identification of the patterns of formation of uroandrological pathology in patients of various age groups against the background of connective tissue failure will provide timely prevention and correction of visceral manifestations of dysplasia in children.

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Section: Introductionmentioning

confidence: 99%