2024
DOI: 10.1101/2024.04.09.588753
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Features of the DNAEscherichia coliRecN interaction revealed by fluorescence microscopy and single-molecule methods

Viktoria D. Roshektaeva,
Aleksandr A. Alekseev,
Alexey D. Vedyaykin
et al.

Abstract: The SOS response is a condition that occurs in bacterial cells after DNA damage. In this state, the bacterium is able to recover the integrity of its genome. Due to the increased level of mutagenesis in cells during the repair of DNA double-strand breaks, the SOS response is also an important mechanism for bacterial adaptation to the antibiotics. One of the key proteins of the SOS response is the SMC-like protein RecN, which helps the RecA recombinase to find a homologous DNA template for repair. In this work,… Show more

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