Features of tinnitus in older patients with autonomic dysfunction

Vladimirova, Tatyana Yu.; Айзенштадт, Л В

doi:10.17116/otorino2021860319

Cited by 3 publications

(3 citation statements)

References 11 publications

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“…Increased sweat volume can occur under conditions of PN, SFN, and sympathetic dysfunction ( 25 ). It has also been reported that TN is frequently observed alongside autonomic dysfunction in older patients ( 26 ). In our study, none of the participants had DM; nonetheless, sweat volumes in PwTNs were higher than those in healthy controls.…”

Section: Discussionmentioning

confidence: 91%

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Abnormal quantitative sudomotor axon reflex test results in patients with tinnitus as a possible indicator of small fiber neuropathy

Lee,

Lyou,

Song

et al. 2024

Front. Neurol.

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A few cases of small fiber neuropathy (SFN) and tinnitus (TN) associated with coronavirus disease 2019 have been reported. However, the relationship between SFN and TN has not been studied. This study investigated a possible relationship between SFN and patients with TN (PwTNs) using autonomic function tests (AFTs) including quantitative sudomotor axon reflex tests (QSART). We performed QSARTs and other AFTs such as the Sympathetic skin response (SSR), Valsalva ratio (VR), and heart rate variability (HRV). The QSART results, obtained at seven hospitals using same protocols, were compared between PwTNs and healthy controls. We confirmed the abnormalities in SSR, VR, and HRV in PwTNs, although those parasympathetic AFTs were not performed in healthy controls. Additionally, we checked Tinnitus handicap inventory (THI) scores for PwTNs and ~50% of PwTNs had low-grade disability, whereas 9.3% had high-grade disability. Data from 57 PwTNs and 122 healthy controls were analyzed. The sweat volumes of QSART in the older age group tended to be higher in the PwTNs than in age-matched healthy controls, and significant differences between the PwTN and control groups were observed in the feet in both sexes (p < 0.001) and in the arms in women (p = 0.013). In the younger age group, the sweat volumes in the feet of men were higher in PwTNs than in healthy controls (p = 0.017). No association was observed between THI and QSART scores. In this study, the sweat volumes in QSARTs were higher in PwTNs than in healthy controls. However, abnormal SSR, HRV, and VR results were not commonly observed in PwTNs. Although the results should be interpreted with caution because of limitations in study, PwTNs might also have SFN apart from dysautonomia. This is the first study to perform QSART with other parasympathetic AFTs in PwTNs. However, larger and more rigorously controlled studies will be needed to reveal the relationship between SFN and TN in the future.

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Section: Discussionmentioning

confidence: 91%

Section: Discussionmentioning

confidence: 95%

Abnormal quantitative sudomotor axon reflex test results in patients with tinnitus as a possible indicator of small fiber neuropathy

Lee,

Lyou,

Song

et al. 2024

Front. Neurol.

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“…The initial state of the central nervous system and any functional disturbances were determined by means of Wayne's questionnaire. [19][20][21][22] The questionnaire refers to 9 parameters, which are evaluated by a doctor during an objective functional examination of the patient. Each parameter is evaluated on a scale of 3-8 points.…”

Section: Determination Of the Cardiovascular System Function And The ...mentioning

confidence: 99%

Changes in the periodontium against the background of systemic vascular reactions in young individuals with obesity

Skrypnyk¹,

Petrushanko²,

Непорада³

et al. 2023

Dent. Med. Probl.

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Background. Overweight and obesity are defined as abnormal or excessive fat accumulation that impairs health. The global prevalence of obesity has been increasing significantly among all age groups. Further more, obesity is a comorbid factor for numerous diseases, including cardiovascular and periodontal pathologies.Objectives. The present study aimed to investigate the influence of overweight and obesity on the peri odontium of young adults in relation to the functional state of the cardiovascular system. Material and methods.The oral health status of 132 males and females aged 18-22 years was exa mined. They were divided into 4 groups according to their body mass index (BMI): normal weight; over weight; class I obesity; and class II obesity. A periodontal chart, the records on oral hygiene and caries, and periodontal indices were provided for each participant. The main functional parameters of the cardiovascu lar system were measured before and after the dental examination.Results. Overweight or obesity did not affect the intensity of caries in young adults. The prevalence and severity of gingivitis were significantly higher in obese individuals. A moderate correlation was found be tween gingivitis and BMI in patients with class I and II obesity. Disturbances in the cardiovascular system function and in the autonomic nervous system tone were also diagnosed in obese patients. An impaired vascular response and significant functional changes in the cardiovascular system developed against the background of obesity. These changes show the development of subcompensation in young adults with obesity.Conclusions. In obese individuals, significantly worse oral hygiene was observed as compared to normal BMI patients. Moreover, the clinical manifestation and intensity of gingivitis in obese individuals were high even in those with satisfactory oral hygiene. In young obese individuals, the periodontal disease mani fested as gingivitis is due to significant adaptive and compensatory mechanisms.

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The use of azithromycin in the treatment of inflammatory diseases of the upper respiratory tract and ear

Ryazantsev,

Vysockaya,

Chernoivan

et al. 2024

Medicinskij sovet

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Despite the extensive accumulated clinical experience, inflammatory diseases of the upper respiratory tract and ear still remain an important problem in the field of otorhinolaryngology, especially pediatric practice, since these diseases are associated with the risk of complications. One of the reasons for the ineffectiveness of conservative treatment is the incorrect initial antibacterial therapy. Errors in antimicrobial therapy are associated with both insufficient knowledge of clinical pharmacology by doctors and incorrect interpretation of anamnestic and clinical data, which leads to incorrect treatment of CCA. The aim of the work is to analyze the use of azithromycin in the treatment of upper respiratory tract and ear infections in children, based on pharmacological characteristics, as well as to consider current methods of antibiotic therapy in pediatric practice. An analysis of the literature and our own observations allows us to conclude that azithromycin is an effective antibacterial drug. Taking into account the low toxicity and good bioavailability, azithromycin continues to be one of the main drugs in the arsenal of doctors for the treatment of various infections, including respiratory diseases and infectious processes of ENT organs in children caused by both typical and atypical bacterial pathogens. The convenient dosage form and simple dosage regimen make this drug a popular choice in outpatient pediatric practice, which confirms the widespread use and trust in this antibacterial drug among both doctors and parents.

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Features of tinnitus in older patients with autonomic dysfunction

Cited by 3 publications

References 11 publications

Abnormal quantitative sudomotor axon reflex test results in patients with tinnitus as a possible indicator of small fiber neuropathy

Abnormal quantitative sudomotor axon reflex test results in patients with tinnitus as a possible indicator of small fiber neuropathy

Changes in the periodontium against the background of systemic vascular reactions in young individuals with obesity

The use of azithromycin in the treatment of inflammatory diseases of the upper respiratory tract and ear

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