Features of vaccination in patients with immunoinflammatory diseases

Abstract

Patients with immune-inflammatory diseases (IID) are a special group of patients at risk of infectious diseases with a probability of a more severe course and outcome. This problem has become more urgent with the emergence of a new coronavirus infection (NCVI) and the need for vaccination against COVID-19. The purpose — to study the features of vaccination against COVID-19 in patients with immune-inflammatory diseases (IID). Material and methods. Conducting surveys and interviews with rheumatological and nephrological patients about vaccination against COVID-19. Results. The study included 225 patients with IID of the Nephrology and Rheumatology Departments of the Republic Clinical Hospital aged 18 to 82 years, among them 133 women and 92 men. Among the 133 women surveyed, 76 (57%) were vaccinated; the main reasons for refusing vaccination were high IID activity and previous NCVI. Among the 92 men surveyed, 59 (64%) were also vaccinated. Just like in women, the main reasons for refusal were high IID activity and previous NCVI. Conclusions. Rheumatological and nephrological patients in general have a rather high (59%) commitment to vaccination against COVID-19. Patients over 35 y.o. were more committed. The main reasons for refusing to be vaccinated were medical withdrawal due to a high activity of the underlying disease and a recent NCVI. In this group of patients, vaccination against COVID-19 was effective and safe; there were no cases of NCVI within 6 months after vaccination.