Febrile Uriniary Tract Infections (fUTI) After Pediatric Kidney Transplantation (pKTx): A Prospective Multicenter Study.

Kemper, Markus J.; Lehnhardt, Anja; Weigel, Friederike; John, U

doi:10.1097/00007890-201407151-00363

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“…Lower urinary tract abnormality is a significant risk factor for UTI after transplant, but UTI was not associated with worsening graft function in a recent study . Recently, a report of a prospective registry of the German Society of Pediatric Nephrology concluded that febrile UTI after kidney transplant is associated with acute morbidity and graft dysfunction; however, this did not result in an accelerated decline of estimated glomerular filtration rate after two yrs .…”

Section: Discussionmentioning

confidence: 99%

Kidney transplant in pediatric patients with severe bladder pathology

Sierralta

González

Nome

et al. 2015

Pediatric Transplantation

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The aim of the current study was to compare results in pediatric renal transplantation of patients with and without SBP. Between 2001 and 2013, a total of 168 kidney transplants were performed at our center. A retrospective analysis was performed and recipients were divided into two groups: NB and SBP. Incidence of surgical complications after procedure, and graft and patient survival were evaluated. A total of 155 recipients (92%) with complete data were analyzed, and 13 recipients that had had previous bladder surgeries were excluded (11 with VUR surgery and two with previous kidney transplants), of the 155 recipients: 123 (79%) patients had NB, and 32 (21%) patients had SBP, with a median follow-up of 60 (1-137) and 52 (1-144) months, respectively. Among post-transplant complications, UTI (68.8% vs. 23%, p < 0.0001) and symptomatic VUR to the graft (40.6% vs. 7.3%, p < 0.0001) were significantly higher in the SBP group. There was no significant difference in overall graft and patient survival between groups. Renal transplantation is safe in pediatric recipients with SBP; however, urologic complications such as UTI and VUR were significantly higher in this group. Graft and patient survival was similar in SBP and NB groups.

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Section: Discussionmentioning

confidence: 99%