Fecal Calprotectin as a Biomarker of Depression Severity: A Systematic Review
Kuljeet K. Chohan,
Bharat Duggal
Abstract:Introduction: Depression is a debilitating mental health condition. Although the underlying pathophysiology of depression is poorly understood, emerging evidence suggests that the gut-brain-immune axis may contribute to depressive symptoms. Recent literature has established that depression is associated with systemic low-grade inflammation. According to the leaky-gut hypothesis, this systemic inflammation is thought to be caused by increased permeability—a by-product of mucosal inflammation. Accordingly, some … Show more
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