2024
DOI: 10.1038/s41598-024-56184-1
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Fecal microbiota impacts development of Cryptosporidium parvum in the mouse

Giovanni Widmer,
Hannah N. Creasey

Abstract: The dependence of Cryptosporidium parasites on host cell metabolites suggests that the development of nutritional interventions to limit parasite proliferation should be feasible. Based on this concept, we are testing dietary interventions to affect the enterocytes’ metabolism in a manner that limits intracellular multiplication of the parasite. We hypothesize that changes in the metabolic pathways encoded by the gastro-intestinal tract microbiota may restrict parasite proliferation. To identify taxonomic and … Show more

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