Fecal-oral transmission of SARS-CoV-2: A systematic review of evidence from epidemiological and experimental studies

Termansen, Martin Brink; Frische, Sebastian

doi:10.1016/j.ajic.2023.04.170

Cited by 25 publications

(8 citation statements)

References 57 publications

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“…It is well known that the transmission of the virus mostly occurs via the upper respiratory tract ( 33 ). Furthermore, it is worth noting that there exists a potential for fecal-oral transmission, since scientific investigations have successfully detected the presence of SARS-CoV-2 in the feces of individuals originating from China and the USA ( 34 ).…”

Section: Discussionmentioning

confidence: 99%

Prevalence and association of oral manifestations with disease severity in patients diagnosed with COVID‑19: A cross‑sectional study

Campeanu,

Rus,

Ispas

et al. 2024

Med Int

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Systemic disorders may exhibit early signs when conducting an oral examination. Since the onset of the CoVID-19 pandemic, several studies have been published detailing the direct impact of the virus on the oral cavity. the present study aimed to determine whether indeed there are any significant disparities in oropharyngeal manifestations between individuals infected with severe acute respiratory syndrome coronavirus 2 and a control group, and whether the virus has the ability to invade and reproduce inside oral keratinocytes and fibroblasts, resulting in the development of oral ulcerations and superficial lesions. The present study provides an overview of the symptoms that occur at an early stage of the illness, and the most commonly affected regions of the oral cavity, including the tongue, lips, palate and oropharynx are examined. In the present retrospective study, 52 patients infected with CoVID-19 were recruited between april, 2021 and october, 2022. In addition, 52 indi-viduals who tested negative for the virus were recruited as the control group. the study was conducted through a thorough examination and questionnaire provided to all participants. the results revealed that among the cohort of patients from the CoVID-19 group examined (n=52), a proportion (mean, 16.15) displayed oral manifestations. Specifically, 75% of the patients in the CoVID-19 group described oral cavity pain, and 69% of these patients had changes in teeth color or dental caries. In summary, in relation to the control group, the prevalence of oropharyngeal symptoms was generally lower compared to the CoVID-19 group, apart from oral cavity pain (30.8%), tonsillitis (17.3%), bleeding (34.6%), teeth color changes (36.5%), recurrence (15.4%) and abscesses (7.7%). thus, on the whole, the patients without CoVID-19 had fewer oral manifestations.

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Section: Discussionmentioning

confidence: 99%

Prevalence and association of oral manifestations with disease severity in patients diagnosed with COVID‑19: A cross‑sectional study

Campeanu,

Rus,

Ispas

et al. 2024

Med Int

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“…Droplet transmission rather than aerosol transmission has been established as the most important mode of transmission [ 101 ]. This is corroborated in animals by the positivity of RT-PCR samples collected within one meter of animal cages on mink farms in Denmark [ 102 ].…”

Section: Viral Transmission and Associated Risksmentioning

confidence: 99%

Perspectives on SARS-CoV-2 Cases in Zoological Institutions

Nederlof,

de la Garza,

Bakker

2024

Veterinary Sciences

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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections in a zoological institution were initially reported in March 2020. Since then, at least 94 peer-reviewed cases have been reported in zoos worldwide. Among the affected animals, nonhuman primates, carnivores, and artiodactyls appear to be most susceptible to infection, with the Felidae family accounting for the largest number of reported cases. Clinical symptoms tend to be mild across taxa; although, certain species exhibit increased susceptibility to disease. A variety of diagnostic tools are available, allowing for initial diagnostics and for the monitoring of infectious risk. Whilst supportive therapy proves sufficient in most cases, monoclonal antibody therapy has emerged as a promising additional treatment option. Effective transmission of SARS-CoV-2 in some species raises concerns over potential spillover and the formation of reservoirs. The occurrence of SARS-CoV-2 in a variety of animal species may contribute to the emergence of variants of concern due to altered viral evolutionary constraints. Consequently, this review emphasizes the need for effective biosecurity measures and surveillance strategies to prevent and control SARS-CoV-2 infections in zoological institutions.

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“…WBS has proven effective for disease monitoring (e.g., for COVID-19 infections), as viral RNA from SARS-CoV-2 is present in the faeces of infected individuals allows for the surveillance of COVID-19 through the quantification of the number of copies of specific genes in the sewage ( Medema et al, 2020 ). Despite concerns over potential SARS-CoV-2 infections from faecal aerosols, a systematic review found no strong evidence of human SARS-CoV-2 faecal-oral transmission ( Termasen and Frische, 2023 ). However, several uncertainties persist.…”

Section: Introductionmentioning

confidence: 99%

Campus source to sink wastewater surveillance of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)

Folkes,

Castro-Gutierrez,

Lundy

et al. 2024

Current Research in Microbial Sciences

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Fecal-oral transmission of SARS-CoV-2: A systematic review of evidence from epidemiological and experimental studies

Cited by 25 publications

References 57 publications

Prevalence and association of oral manifestations with disease severity in patients diagnosed with COVID‑19: A cross‑sectional study

Prevalence and association of oral manifestations with disease severity in patients diagnosed with COVID‑19: A cross‑sectional study

Perspectives on SARS-CoV-2 Cases in Zoological Institutions

Campus source to sink wastewater surveillance of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)

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