Feedback control of electrode offset voltage during functional electrical stimulation

Chu, Jun Uk; Song, Kang Il; Shon, Ahnsei; Han, Sungmin; Lee, Soo Hyun; Kang, Ji Yoon; Hwang, Dosik; Suh, Jin‐Yoo; Choi, Kuiwon; Youn, Inchan

doi:10.1016/j.jneumeth.2013.05.003

Cited by 5 publications

(5 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Table 2 provides a comparison between our system and other neurostimulators. Previous studies used a non-programmable charge injection (manually with an analog potentiometer) on a single channel and external oscilloscope to monitor voltage responses [ 17 , 18 ]. Our system offers unique and key combinations of features such as programmable anodic bias control, multichannel constant-current stimulations, and voltage transients monitoring with a built-in wireless bidirectional data transmission.…”

Section: Discussionmentioning

confidence: 99%

“…Previously, bias voltage was often set by operating an analog potentiometer with feedback circuitry in the pulse generator to control an offset voltage across the stimulating electrodes [ 17 , 18 ]. However, analog potentiometers with carbon-composition resistors (having an error tolerance of at least 1% [ 25 ]) and a rotatable contact with manual control have low voltage adjustment precision.…”

Section: Introductionmentioning

confidence: 99%

“…An alternative technique to increase the charge injection capacity of the microelectrode is by applying an anodic bias potential [16][17][18][19][20]. It is known that certain microelectrodes become more conductive when their initial potential is elevated (mostly 0.4 V-0.8 V vs. Ag|AgCl), and iridium oxide electrodes (IrO x ) in particular become more conductive by conditioning Ir 3+ into Ir 4+ valence state [8].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

A portable neurostimulator circuit with anodic bias enhances stimulation injection capacity

2022

View full text Add to dashboard Cite

Objective: Electrochemically safe and efficient charge injection for neural stimulation necessitates monitoring of polarization and enhanced charge injection capacity of the stimulating electrodes. In this work, we present improved microstimulation capability by developing a custom-designed multichannel portable neurostimulator with a fully programmable anodic bias circuitry and voltage transient monitoring feature. Approach: We developed a sixteen-channel multichannel neurostimulator system, compared charge injection capacities as a function of anodic bias potentials, and demonstrated convenient control of the system by a custom-designed user interface allowing bidirectional wireless data transmission of stimulation parameters and recorded voltage transients. Charge injections were conducted in phosphate-buffered saline with silicon-based iridium oxide microelectrodes. Main Results: Under charge-balanced 200 µs cathodic first pulsing, the charge injection capacities increased proportionally to the level of anodic bias applied, reaching a maximum of ten-fold increase in current intensity from 10 µA (100 µC/cm2) to 100 µA (1000 µC/cm2) with a 600 mV anodic bias. Our custom-designed and completely portable sixteen-channel neurostimulator enabled a significant increase in charge injection capacity in vitro. Significance: Limited charge injection capacity has been a bottleneck in neural stimulation applications, and our system may enable efficacious behavioral animal study involving chronic microstimulation while ensuring electrochemical safety.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

A portable neurostimulator circuit with anodic bias enhances stimulation injection capacity

2022

View full text Add to dashboard Cite

show abstract

“…Figure 4 shows the voltage-controlled current source (VCCS) that was used for neural stimulation. The current source should provide a sufficiently large output impedance and a minimized output current error should be guaranteed over a wide range of stimulation frequencies [ 33 , 34 ]. To maintain these conditions, a dual operational-amplifier current source was used as the current source.…”

Section: Methodsmentioning

confidence: 99%

An Implantable Wireless Neural Interface System for Simultaneous Recording and Stimulation of Peripheral Nerve with a Single Cuff Electrode

Shon

Chu

Jung

et al. 2017

Sensors

Self Cite

View full text Add to dashboard Cite

Recently, implantable devices have become widely used in neural prostheses because they eliminate endemic drawbacks of conventional percutaneous neural interface systems. However, there are still several issues to be considered: low-efficiency wireless power transmission; wireless data communication over restricted operating distance with high power consumption; and limited functionality, working either as a neural signal recorder or as a stimulator. To overcome these issues, we suggest a novel implantable wireless neural interface system for simultaneous neural signal recording and stimulation using a single cuff electrode. By using widely available commercial off-the-shelf (COTS) components, an easily reconfigurable implantable wireless neural interface system was implemented into one compact module. The implantable device includes a wireless power consortium (WPC)-compliant power transmission circuit, a medical implant communication service (MICS)-band-based radio link and a cuff-electrode path controller for simultaneous neural signal recording and stimulation. During in vivo experiments with rabbit models, the implantable device successfully recorded and stimulated the tibial and peroneal nerves while communicating with the external device. The proposed system can be modified for various implantable medical devices, especially such as closed-loop control based implantable neural prostheses requiring neural signal recording and stimulation at the same time.

show abstract

“…Alternate to having complex digital processing capability, it would be appropriate to implement them in the analog domain. An analog implementation of the P-I controller based charge balance scheme in nerve cuff stimulators is reported in [12]. However the design reported is carried out using discrete 'commercial off the shelf' components.…”

Section: Introductionmentioning

confidence: 99%

PI controller scheme for charge balance in implantable electrical stimulators

Rathna¹

2016

Sadhana

View full text Add to dashboard Cite

Electrical stimulation has been used in a wide variety of medical implant applications. In all of these applications, due to safety concerns, maintaining charge balance becomes a critically important issue that needs to be addressed at the design stage. It is important that charge balancing schemes be robust to circuit (process) and load impedance variations, and at the same time must also lend themselves to miniaturization. In this communication, simulation studies on the effectiveness of using Proportional Integral (P-I) control schemes for managing charge balance in electrical stimulation are presented. The adaptation of the P-I control scheme to implant circuits leads to two possible circuit realizations in the analog domain. The governing equations for these realizations are approximated to simple linear equations. Considering typical circuit and tissue parameter values and their expected uncertainties, Matlab as well as circuit simulations have been carried out. Simulation results presented indicate that the tissue voltages settle to well below 20% of the safe levels and within about 20 stimulations cycles, thus confirming the validity and robustness of the proposed schemes.

show abstract

Feedback control of electrode offset voltage during functional electrical stimulation

Cited by 5 publications

References 19 publications

A portable neurostimulator circuit with anodic bias enhances stimulation injection capacity

A portable neurostimulator circuit with anodic bias enhances stimulation injection capacity

An Implantable Wireless Neural Interface System for Simultaneous Recording and Stimulation of Peripheral Nerve with a Single Cuff Electrode

PI controller scheme for charge balance in implantable electrical stimulators

Contact Info

Product

Resources

About