This research presents a comprehensive usability evaluation of Pathpoint eDerma Software, conducted in accordance with IEC 62366-1:2015 standards. The study encompasses four diverse user groups, that includes administrators, medical photographers, dermatologists, and patients, ensuring a holistic assessment of the software's usability and effectiveness. Through a combination of quantitative metrics and qualitative feedback, the study explores various aspects such as accessibility, navigation, safety, and user satisfaction. Potential risks to user experience and patient data security are identified and addressed to ensure compliance with safety standards. The findings highlight the software's effectiveness in facilitating remote assessments, streamlining workflows, and improving patient care. This research contributes valuable insights to the ongoing refinement and optimisation of eDerma Software, aiming to enhance its usability, safety, and overall effectiveness in real-world healthcare settings.