Feeding a diet contaminated with ochratoxin A for broiler chickens at the maximum level recommended by the <scp>EU</scp> for poultry feeds (0.1 mg/kg). 2. Effects on meat quality, oxidative stress, residues and histological traits

Pozzo, Luisa; Cavallarin, Laura; Antoniazzi, Sara; Guerre, Philippe; Biasibetti, Elena; Capucchio, Maria Teresa; Schiavone, Achille

doi:10.1111/jpn.12051

Cited by 22 publications

(15 citation statements)

References 44 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Moreover, the OTA‐treated chickens showed a lower absolute spleen weight. These findings are in accordance with the histopathological observations presented in Part 2 of the present study (Pozzo et al., ) that showed an increase in apoptosis in the splenic follicles of OTA‐treated chickens. It is known that the immunosuppressant activity of OTA is characterized by a reduction in size of the vital immune organs (Al‐anati and Petzinger, ).…”

Section: Discussionsupporting

confidence: 94%

Feeding a diet contaminated with ochratoxin A for chickens at the maximum level recommended by the EU for poultry feeds (0.1 mg/kg). 1. Effects on growth and slaughter performance, haematological and serum traits

Pozzo

Salamano

Mellia

et al. 2013

Animal Physiology Nutrition

Self Cite

View full text Add to dashboard Cite

SummaryThe European Commission Recommendation 2006/576/EC, suggests that the maximum level of Ochratoxin A (OTA) in poultry feeds should be set at 0.1 mg OTA/kg. Thirty-six one-day-old male Hubburd broiler chickens were divided into two groups, a Control (basal diet) and an Ochratoxin A (basal diet + 0.1 mg OTA/kg) group. The growth and slaughter performance traits were recorded. The liver, spleen, bursa of Fabricius and thymus weights were measured. The erythrocyte and leukocyte numbers were assayed in blood samples, and the heterophils to lymphocytes (H/L) ratio was determined. Alpha-1-acid glycoprotein (AGP), lysozyme, the total protein and the electrophoretic pattern were evaluated in serum samples. Liver enzymes (alanino aminotransferase, ALT and aspartate aminotransferase, AST) and kidney function parameters (uric acid and creatinine) were quantified. The results revealed that feeding a 0.1 mg OTA/kg contaminated diet to chicks caused a decrease in the absolute thymus weight (p < 0.05) and a lower total protein (p < 0.01), albumin (p < 0.01), alpha (p < 0.05), beta (p = 0.001) and gamma (p = 0.001) globulins serum concentration in the Ochratoxin A group. Moreover, the albumin-to-globulin (A/G) ratio of the OTA-treated animals resulted to be higher (p < 0.05). Feeding broiler chickens, a diet contaminated with the maximum level admitted by the European Commission Recommendation (0.1 mg OTA/kg), did not affect the animal performance, slaughter traits, organ weights, haematological parameters, liver enzyme or renal function parameters concentrations but had an overall immunosuppressant effect, with reduction in the thymus weight and of the total serum protein, albumin, alpha, beta and gamma globulins concentration.

show abstract

Section: Discussionsupporting

confidence: 94%

Feeding a diet contaminated with ochratoxin A for chickens at the maximum level recommended by the EU for poultry feeds (0.1 mg/kg). 1. Effects on growth and slaughter performance, haematological and serum traits

Pozzo

Salamano

Mellia

et al. 2013

Animal Physiology Nutrition

Self Cite

View full text Add to dashboard Cite

show abstract

“…In the study of Pozzo et al, OTA residues were detected in kidneys (3.58 ng/g) and liver (1.92 ng/g) of broiler chickens receiving OTA contaminated mixtures in the amount of 0.1 mg/kg [ 33 ]. Similar results were obtained in other studies [ 34 , 35 ].…”

Section: Resultsmentioning

confidence: 99%

The Effect of Using New Synbiotics on the Turkey Performance, the Intestinal Microbiota and the Fecal Enzymes Activity in Turkeys Fed Ochratoxin A Contaminated Feed

Śliżewska

Markowiak‐Kopeć

Sip

et al. 2020

Toxins

View full text Add to dashboard Cite

The feed supplementation of probiotic microorganisms is a promising method for detoxification of ochratoxin A (OTA) in poultry. The aim of the study was to investigate the effect of newly elaborated synbiotics on the turkey performance, the intestinal microbiota and its enzymatic activity in turkeys (0–15 weeks) fed OTA contaminated feed (198.6–462.0 µg/kg) compared to control group (OTA-free feed). The studies determined the composition of intestinal microorganisms by the culture method and the activity of fecal enzymes by spectrophotometry. It was found that OTA had an adverse effect on the body weight, the intestinal microbiota and the fecal enzymes activity in turkeys. On the other hand, synbiotics resulted in an increase in the count of beneficial bacteria while reducing the number of potential pathogens in the digestive tract. Moreover, synbiotics caused an increase in the activity of α-glucosidase and α-galactosidase, while decreasing the activity of potentially harmful fecal enzymes (β-glucosidase, β-galactosidase, β-glucuronidase) in the turkey’s excreta. Results indicate a beneficial effect of elaborated synbiotics on the health of turkeys and a reduction of the negative impact of OTA contaminated feed. These synbiotics can be successfully used as feed additives for turkeys.

show abstract

“…Young chickens are more susceptible to the trans-epithelium migration of pathogens [ 22 ]. Usually, liver and kidney damage are linked to aflatoxin [ 48 ] and ochratoxin A [ 49 ] exposure. However, neither of these mycotoxins was detected in the diets.…”

Section: Discussionmentioning

confidence: 99%

Susceptibility of Broiler Chickens to Deoxynivalenol Exposure via Artificial or Natural Dietary Contamination

Santos

Doelen

Tersteeg-Zijderveld

et al. 2021

Animals

View full text Add to dashboard Cite

Multi-mycotoxin contamination of poultry diets is a recurrent problem, even if the mycotoxins levels are below EU recommendations. Deoxynivalenol (DON) is one of the main studied mycotoxins due to its risks to animal production and health. When evaluating the effects of DON, one must consider that under practical conditions diets will not be contaminated solely with this mycotoxin. In the present study, broiler chickens were fed diets with negligible mycotoxin levels or with naturally or artificially contaminated diets containing approximately 4000 μg/kg DON. Birds were sampled at D14 and D28. Naturally-contaminated diets caused the most harm to the birds, especially the young ones, which presented decreased jejunal villus height and increased lesions, down-regulation of a peptide transporter. At D28 broiler chickens seemed to have adapted to the dietary conditions, when no differences were observed in villus morphometry, together with up-regulation of a carbohydrate transporter. However, intestinal lesions remained present in these older birds.

show abstract

Feeding a diet contaminated with ochratoxin A for broiler chickens at the maximum level recommended by the EU for poultry feeds (0.1 mg/kg). 2. Effects on meat quality, oxidative stress, residues and histological traits

Cited by 22 publications

References 44 publications

Feeding a diet contaminated with ochratoxin A for chickens at the maximum level recommended by the EU for poultry feeds (0.1 mg/kg). 1. Effects on growth and slaughter performance, haematological and serum traits

Feeding a diet contaminated with ochratoxin A for chickens at the maximum level recommended by the EU for poultry feeds (0.1 mg/kg). 1. Effects on growth and slaughter performance, haematological and serum traits

The Effect of Using New Synbiotics on the Turkey Performance, the Intestinal Microbiota and the Fecal Enzymes Activity in Turkeys Fed Ochratoxin A Contaminated Feed

Susceptibility of Broiler Chickens to Deoxynivalenol Exposure via Artificial or Natural Dietary Contamination

Contact Info

Product

Resources

About